Job - Postdoc, Faculty of Health, Medicine and Life Sciences / Department of Internal Medicine / Division of Haematology

It concerns a Dutch cancer foundation subsidized project where the postdoc will collaborate with a PhD student and a technician. The aim is to generate in vitro immune competent T cells from CD34+ stem cells in a stroma cell free system under GMP conditions. The generated progenitor T cells will be injected into humanized mice and the mechanism of their thymus homing capcity will be elucidated. Furthermore the project comprises studies to further maturation of progenitors to adult T cells, including the use of retroviral transduction of antigen specifc T cell receptors. Finally, thymus rejuvination to better host injected progenitors will be inverstigated. In the project collaborations exist with groups in Zurich, Amsterdam and Yokohama en the possibility exist to carry out experiments in those locations.

We are looking for somebody with a (bio)medical education as well as a PhD in Immunology, preferably T cell biology/thymus. You will have affinity to translational research and collaboration in a small team. Preferably you will have experience in molecular biology, cell biology as well as affinity and experience in murine animal models.

The terms of employment of Maastricht University are set out in the Collective Labour Agreement of Dutch Universities (CAO). Furthermore, local UM provisions also apply. For more information look at the website http://www.maastrichtuniversity.nl/ , A-Z Terms of Employment.

GROW focuses on research and teaching of (epi)genetic, cellular and (micro)environmental factors and mechanisms underlying normal (embryonic and fetal) and abnormal (cancer) development, with emphasis on translational research aiming at innovative approaches for individualizing prevention, patient diagnostics and treatment.

If you want more information do not hesitate to contact Dr. W.T.V. Germeraad (+31-(0)43-3884300) or Dr. G.M.J. Bos (+31-(0)43-3877026).