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PhD Development of a sensor for biomarker detection

Specifications - (explanation)

Function types	PhD positions
Scientific fields	Natural Sciences
Hours	38.0 hours per week
Education	University Graduate
Job number	AFSG-ORC-0006
Translations	en

Job has expired

Job description

In the collaborative project “Brainlabs” between WageningenUniversity, University Medical Center Groningen and 4 companies (Brainlabs, Zebra Bioscience, Lionix and Bohlmeijer Holding) the Laboratory of Organic Chemistry is looking for a PhD student who will perform research on the local covalent immobilization of different antibodies in a new type of multiplex sensor. The microfluidic array-like sensor should be capable of rapid detection of biomarkers whose occurrence in plasma or urine is linked to various forms of depression in humans. The work includes the specific local chemical modification of chips with suitable spacers to which antibodies against the biomarkers will be bound. After developing a suitable sample clean-up, multiple samples will be analyzed simultaneously for multiple biomarkers. Validation of the sensor with regard to selectivity, sensitivity and robustness will be part of the work. The PhD student will closely cooperate with other scientists involved in this project.

In the collaborative project “Brainlabs” between Wageningen University, University Medical Center Groningen and 4 companies (Brainlabs, Zebra Bioscience, Lionix and Bohlmeijer Holding) the Laboratory of Organic Chemistry seeks a PhD student who will perform research on the local covalent immobilization of different antibodies in a new type of multiplex sensor.

Requirements

Suitable candidates should have an MSc in Molecular Sciences/Chemistry/Pharmacy, and demonstrated eagerness to propel the frontiers of knowledge. Experience with organic surface modification and characterization, sample pretreatment and/or microfluidics is a plus.

Conditions of employment

We offer you a temporary position for a period of 1.5 years with extension of 2.5 years after successful evaluation. Gross salary per month € 2042 in the first year rising up to € 2612 per month in the fourth year.

We not only offer a competitive salary but also good (study) leave and a pension of the ABP Pension Fund.

Wageningen UR uses a so-called cafeteria model (Optare) that makes it possible to vary the conditions of employment.

We think it is important to have a good balance between work and private life. Depending on the specific job and working place, this balance can be made possible in various ways, for example, flexible working hours, working part time or the possibility of taking sabbatical leave.

For more information about the project please contact Prof.dr. H. Zuilhof, tel +31 317-482361 or Dr. T.A. van Beek, tel. +31 317-482376.
For information about the contractual aspects please contact Mrs. N. de Vries, HRM , AFSG, tel +31 317-485677.

Interested?
You can apply online until August 4th 2010 at www.werkenbij.wur.nl

Contract type: Temporary,

Organisation

Wageningen UR (University & Research centre)

Wageningen University and Research centre (Wageningen UR) is a leading international organization. Within the field of healthy nutrition and living environment we are working on the quality of life. We are always looking for talented colleagues. Professionals with passion who want to work with us for the world of tomorrow.

Agrotechnology and Food Sciences is the organization for development and transfer of knowledge in the field of sustainable applications of agro-components for safe and healthy food and non-food products.

The Organic Chemistry group (www.orc.wur.nl) constitutes a large, interdisciplinary research team involved in teaching and research on organic chemistry, with an emphasis on surface-based reactivity. Examples that gained international recognition include biofunctionalized organic monolayers and microchannels, immobilized enzymes, and bio-organic nanoparticles. The group aims to excel in the research and teaching of organic chemistry. The laboratory is well-equipped with a unique set of analysis instruments for bio-organic materials and surfaces, and has an experienced technical staff. In addition to this, the embedding within Wageningen University and Research Centre adds ample biological input into our focus on chemistry-based bionano-technology. Currently ca. 1000 students/year take part in one or more Organic Chemistry study elements provided by our faculty.

Additional information

AFSG-vacatures@wur.nl

More information about employer Wageningen UR (University & Research centre) on AcademicTransfer. Direct link to this job opening: www.academictransfer.com/5565

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