You will work on a project that aims to elucidate factors that play a role in determining the efficiency of therapeutic exon skipping compounds for Duchenne muscular dystrophy. The project is funded by and in collaboration with Sarepta Therapeutics. You will work in a team consisting of a professor, an assistant professor, two postdocs, two PhD students and four technicians, that focuses on developing therapies for muscular dystrophies with a focus on Duchenne. Your work will involve testing different exon skipping compounds in muscle cell cultures and evaluating parameters that influence efficiency.

You are a highly motivated candidate who has recently obtained a PhD degree in molecular biology or a similar subject. You have an interest in Duchenne muscular dystrophy and muscular diseases in general. Also, you are interested in academic research and collaborating in research projects. You have experience with cell culture, additional experience with muscular cell culturing is preferred. Furthermore, you have experience with common molecular biological techniques. Finally, you possess solid communication skills.

Fixed-term contract: 1 year.

You will be employed on the basis of 36 hours per week. Appointment is for one year, possibly to be extended. Your salary is based on your education and experience and is a maximum of  € 4,481 gross per month, based on a full time position (scale 10 in the Collective Labour Agreement for University Hospitals).

LUMC

At the Leiden University Medical Center, we continuously work on improving patient care. We invest in groundbreaking, international research and work with the latest equipment. Together with our team of doctors, medical specialists, teachers, academic researchers and supporting staff, we aim for the best quality in health care, education and international research. And we need you to realize our goals!

The Department of Human Genetics

The Department of Human Genetics is a broadly oriented research department, led by Professor Silvère van der Maarel. The department focuses on the genetic aspects of monogenic, multifactorial and acquired diseases, and the translation into clinical relevance. The department consists of 21 research units, embedded in four overarching research themes. You will work in the group led by prof. dr. Annemieke Aartsma-Rus.