The Eindhoven University of Technology (TU/e) is seeking a bright PhD candidate to investigate the mechanobiology of synthetic-tissue morphogenesis. The PhD will investigate the role of cell mechanics in the (mal)formation and (mal)function of synthetic tissues, which emerges at the mesoscale between cellular units and their collectives via cell-cell and cell-matrix interactions. Doctoral research will be part of wider and exciting efforts currently spearheaded within the
Synthetic-Morphogenesis group.
Eindhoven University of TechnologyTU/e is a University of Technology with a focus on Health, Energy and Mobility. Within the Health area, several departments cooperate on topics such as Chemical Biology, Regenerative Medicine, Computational Biology, and Biosensing, with close links to healthcare and industry. TU/e is an open and inclusive university with short communication lines. The people are curious, collaborative, and strive for excellence. TU/e enables its academic staff to develop research and education at an internationally renowned level. Our lively campus community facilitates connections between staff and students, in an open, friendly, vibrant atmosphere that welcomes and inspires.
Biomedical EngineeringThe Department of Biomedical Engineering (BME) offers a research driven BME Bachelor program and Masters in Biomedical Engineering and Medical Engineering in its Graduate Program. Its research areas range from Molecular Bioengineering and Imaging, Biomechanics and Tissue Engineering to Biomedical Imaging and Modelling. The department has more than 800 students and up to 200 tenured and non-tenured employees.
Job descriptionThe candidate will generate unprecedented in vitro models and experimental data to understand the physical basis of synthetic-tissue morphogenesis in physiological and pathological conditions. The in vitro experimental methods involved in this inquiry may include: i) Cell Traction Microscopy, Laser Ablation and Advanced Image Analyses for the quantification of cell and tissue mechanics; and, ii) Molecular and Cell Biology techniques as well as 2D/3D Co-culture for the manipulation of both cellular genotype and phenotype. The candidate will build on established experimental protocols as well as create new ones in order to further develop new methodological approaches for the handling of novel experimental setups currently unavailable in the field. The PhD candidate is expected to do scientific research in the field described above, write a doctoral thesis and publish research results in scientific journals. An educational and professional development program is offered to all PhD candidates by the TU/e. A small part of the position involves teaching in courses offered by the group.