The computational chemistry and physics group and the analytical chemistry group, both at the Van ‘t Hoff Institute for Molecular Sciences in the Faculty of Science of the University of Amsterdam (UvA), are looking for a talented and dedicated researcher to join a challenging project on predicting the effect of ions on the multimerization properties of an industrially relevant enzyme.

What are you going to do?

The project aims to understand the effect of ion type and concentration on the conformation and multimerization properties of beta-galactosidase, an industrially relevant enzyme. You will develop a molecular simulation protocol to compute the affinity of β-galactosidase for ions, which will be employed to predict the effects of ions on the dimerization and tetramerization properties of β-galactosidase. The predictions will be tested by AF4-MALS experiments.

• A PhD in Chemistry;
• a strong expertise in molecular dynamics simulations;
• demonstrated experience in molecular simulation of proteins;
• experience in performing rare event simulations;
• fluency in English, both written and spoken.

Our offer

A temporary contract for 38 hours per week, preferably starting at 1 July 2020 for the duration of 20 months.    

The salary, depending on relevant experience before the beginning of the employment contract, will be €2,709 to €4,274 (scale 10) gross per month, based on a full-time contract (38 hours a week). These amounts are exclusive 8 % holiday allowance and 8,3% end-of-year bonus. A favourable tax agreement, the ‘30% ruling’, may apply to non-Dutch applicants. The Collective Labour Agreement of Dutch Universities is applicable.

Are you curious about our extensive package of secondary employment benefits like our excellent opportunities for study and development? Then find out more about working at the Faculty of Science.

University of Amsterdam

With over 5,000 employees, 30,000 students and a budget of more than 600 million euros, the University of Amsterdam (UvA) is an intellectual hub within the Netherlands. Teaching and research at the UvA are conducted within seven faculties: Humanities, Social and Behavioural Sciences, Economics and Business, Law, Science, Medicine and Dentistry. Housed on four city campuses in or near the heart of Amsterdam, where disciplines come together and interact, the faculties have close links with thousands of researchers and hundreds of institutions at home and abroad.  

The UvA’s students and employees are independent thinkers, competent rebels who dare to question dogmas and aren’t satisfied with easy answers and standard solutions. To work at the UvA is to work in an independent, creative, innovative and international climate characterised by an open atmosphere and a genuine engagement with the city of Amsterdam and society.

Faculty of Science - Van't Hoff Institute for Molecular Sciences

The Faculty of Science has a student body of around 6,500, as well as 1,600 members of staff working in education, research or support services. Researchers and students at the Faculty of Science are fascinated by every aspect of how the world works, be it elementary particles, the birth of the universe or the functioning of the brain.

The Van't Hoff Institute for Molecular Sciences (HIMS) is located at the vibrant Amsterdam Science Park. HIMS is one of eight institutes of the Faculty of Science. With around 140 employees, HIMS carries out internationally high-quality chemical research and provides education within various university programmes.ation-oriented research with private (co-) funding.