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The group of Dr. Juan Garaycoechea currently has a vacancy for a technician to work on Mechanisms of physiological mutagenesis.
Description of the project
DNA carries the instructions of life, but is also under constant attack. The resulting damage, if not repaired, leads to mutation and disease. Common environmental mutagens include sunlight and cigarette smoke, but the integrity of DNA is also threatened by chemicals produced by our own body. Our lab seeks to understand the metabolic sources of DNA damage and molecular mechanisms that lead to mutagenesis in a physiological setting. In order to do this, we will develop methods to quantify mutation in somatic tissue and use genetics in a number of systems, including mice, to gain mechanistic insight into the process that drive this.
We are looking for a highly motivated and skilled technician with an HLO background and experience with molecular biology and cell culture methods. Experience with Next Generation Sequencing and library preparation is advantageous. The ideal candidate also has experience with animal experimentation or article 9 qualification. The working language in our international team is English, the candidate should therefore have excellent English communication skills and be able to work as part of a team.
Duration
Initially six months with a potential extension.
Salary
According to “CAO-Nederlandse Universiteiten” (CAO-NU), depending on experience scale 7 or 8, excluding 8% holiday allowance and an 8.3% year-end bonus. We offer an extensive package of fringe benefits.
Starting date
October 1st, 2021
The Hubrecht Institute is a research institute focusing on developmental and stem cell biology. It encompasses 24 research groups that perform fundamental and multidisciplinary research, both in healthy systems and disease models. The Hubrecht Institute is a research institute of the Royal Netherlands Academy of Arts and Sciences (KNAW)., located on the Utrecht Science Park ‘De Uithof’. Since 2008, the institute has been affiliated with the University Medical Center Utrecht, advancing the translation of research into clinical practice. The Hubrecht Institute has a partnership with the European Molecular Biology Laboratory (EMBL).
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