We are keen to meet candidates for two positions in translational biomedical research for in vivo imaging of lipids in atherosclerosis. Atherosclerosis is the largest single cause of death worldwide, and today's treatment options do not account for individual differences, reducing their efficacy. Capitalizing on combined optical spectroscopy and ex-vivo molecular imaging, we aim to develop advanced biochemical diagnostic technologies to guide personalized therapies in patients with atherosclerosis. The full project team will comprise 5-6 people and is embedded in the Biomedical Engineering group, part of the Department of Cardiology.

As a PhD candidate/ Junior researcher you will develop catheter-based optical spectroscopic lipid imaging of atherosclerotic plaques, occurring in the coronary vessels. The presence, distribution and molecular composition of lipids in atherosclerosis provides insight in disease development and may predict future heart attacks. The project involves the design, assembly and optimization of a custom optical coherence tomography system, development of lipid spectroscopy with phantoms and ex vivo tissues, and evaluation of the performance of this system in a clinical setting.

You have obtained an MSc degree in (Applied) Physics, Electronics, Biomedical Engineering, or a related discipline. You have a can-do attitude and are an able experimentalist. Experience in optics, lasers or biophysics is a definite asset. The research project should result in a PhD thesis. Expertly qualified postdoc candidates are also invited to apply. In this case, you hold a PhD in a closely related field, and your qualities as a scientist are evident from your publications.

Being able to present a certificate of good conduct, a valid proof of identity, diploma's and/ or relevant registration such as BIG/ RGS are conditions for the appointment.

You will receive a temporary position for 4 years. The gross monthly salary is € 2.279,- in the 1st year and increases to € 2.919,- in the 4th year (scale OIO). The terms of employment are according to the Collective Bargaining Agreement for Dutch University Medical Centers (CAO UMC).

Erasmus MC

Erasmus MC stands for a healthy population and excellence in healthcare. By conducting groundbreaking work, we aim to push boundaries through leading the way in research, education and healthcare. We have access to the latest equipment and techniques in a state-of-the-art environment.

Thoraxcenter Biomedical Engineering is part of Thoraxcenter, Erasmus MC. The research groupd is led by Prof.dr. ir. A. F. W. van der Steen. At the crossroads of Physics, Technology, Biology and Medicine we are developing inovative techniques and methods to enhance insights to improve diagnosis and treatment of cardiovascular diseases.