Clinical and lab setting: the pediatric surgical center of Amsterdam, comprises both university medical centers of Amsterdam (AMC and VUMC) and its lab at the Tytgat Institute for liver and intestinal research in Amsterdam. At the Center, a tenure track position is available as of Q2-3 2018.

The Assistant Professor is expected to unravel the pathophysiology of intestinal failure in neonates and children, including necrotizing enterocolitis, and Hirschsprung’s disease, with special focus on neonatal nutrition and intestinal maturation.

Area of research: The tenure will be building on a large cohort of pre-term, and neonatal samples to study intestinal development and disease early in life. State of the art facilities to analyze microbial, fungal composition, and metabolic profiles during development and during intestinal failure in the term and preterm neonate. Main focus is to understand the healthy development of the neonatal bowel, and the later life health risks that coincide pre-term birth.

Facilities: next to the general AMC-VUMC core, the laboratory has extensive facilities to study organoid and gut-on a chip platforms, next gen sequencing facilities, an imaging suite, and a platform for metabolomics analyses. The Tytgat Institute harbors the state of the art in gastroenterology and hepatology research, and offers unique (>70FTE) GI-focused research lab space and facilities.

The position: the Assistant Professor is expected to build up a research-line together with the pediatric surgeons and two new PhD students. In this role, a permanent position is available upon pre-established deliverables, where the candidate will be responsible for the translational experimental research of pediatric surgery.

• (Recent) Ph.D. degree in (medical) biology, Medicine, Molecular Life Sciences, Health Sciences or related discipline

• Experience with molecular & cell biological techniques, cell/tissue culture

• Experience with animal research (art.9 is preferable)

• Independent, creative, and well-structured working style

• A strong track record of publications and obtained grants demonstrating excellence and strong motivation to succeed in scientific research

• Well-developed social skills directed to work in a team (looking beyond boundaries of his/her own scope)

• Interest in basic, and translational research

• Good verbal and written communication skills in English

  Coaching/supervision of PhD-students, laboratory colleagues and students is an inherent aspect of the role.

We offer a full time (36h) tenure position. After positive evaluation after the first and second year, a permanent position is an option. 

You will be employed by the AMC Medical Research BV. The gross salary will be € 2.659,00 - € 4.216,00 per month. In addition the AMR BV has an end of year bonus of 8.3% and a holiday payment of 8% of the gross yearly salary.

AMC Medical Research

The AMC is more than just a hospital. It is a world in which patient care, research and education are integrated, and in which people are always central. It is an academic world full of possibilities for talented individuals that are looking for a place where they can excel. Thinking big, daring to dream, cooperating internationally. And never letting yourself be put off by ‘It’s not possible’ or ’It won’t work anyway’. That is the AMC mentality.

http://www.amc.nl/

The AMC is more than just a hospital. It is a world in which patient care, research and education are integrated, and in which people are always central. It is an academic world full of possibilities for talented individuals that are looking for a place where they can excel. Thinking big, daring to dream, cooperating internationally.

The 2 universities in Amsterdam (AMC and VUMC) collaborate in one pediatric surgical center, caring for neonates and children from a large part of the Netherlands. The pediatric surgical center of Amsterdam is an all-round center with nine pediatric surgeons, taking care for patients from the antenatal phase towards adolescence.

Intestinal and liver research of the AMC is concentrated in the Tytgat Institute for Liver and Intestinal Research (affiliated with the Department of Gastroenterology & Hepatology) and this will be your workplace. Daily supervision will be by Prof. Wouter de Jonge (see http://www.gut-research.com) together with Prof. Ernest van Heurn and Dr. Joep Derikx. Housing more than 70 basic and clinical scientists, we are one of the leading international research centers in gastroenterology and hepatology. Research in the Tytgat Institute is both fundamental and translational, but always built on a clinical question, providing results that can be translated into clinical practice. Extensive collaboration between physicians and researchers ensures a close link between the clinic and basic research.