Our group investigates the mechanisms underlying the precise wiring of the brain. Our goal is to identify the early activity patterns and plasticity mechanisms that are responsible for fine-tuning synaptic connections in the developing cortex and, eventually, preparing the brain for sensory perception. In the adult cortex, neurons perform high-level computations. However, how cortical neurons get wired into networks during development such that they can perform these computations is currently unknown. This question is addressed by the project “The fundamental logic of fine-scale connectivity in the developing cortex”, funded by an ALW Open Program Grant. The successful candidate will use in vivo imaging to measure directly the function and plasticity of developing synapses in vivo. Furthermore, he/she will apply brain clearing techniques and whole-brain immunohistochemistry to reveal the molecular nature of functionally characterized synapses.

We are looking for a scientist with a strong interest in neuronal development and physiology and the ambition to learn in vivo imaging. The ideal candidate will have experience with electrophysiological approaches, in particular patch-clamping. Proficiency in English and programing skills are required

The position involves a fulltime temporary appointment for two years. The salary will be commensurate with experience and institutional guidelines based on the Collective Labour Agreement for Dutch Universities (CAO NU). We provide an 8% holiday allowance and 8.3% year-end bonus. In addition, we offer an extensive package of fringe benefits.

NIN - KNAW

The Netherlands Institute for Neuroscience (NIN) is an institute of the Royal Netherlands Academy of Arts and Sciences (KNAW). The NIN carries out fundamental and strategic research in the neurosciences with an emphasis on research of the brain and the visual system.