Project description

The EU/FP7 HeCaTos project (Hepatic and Cardiac Toxicity Systems modeling) aims to develop in silico models for predicting heart and liver toxicity, by incorporating ‘omics and functional data from dedicated in vitro cell systems and patient materials.

As a PhD student you will work on analyzing cross-omics data generated by next generation sequencing and mass spectrometry in combination with techniques to capture effects of oxidative stress and help to convert these into testable models. You will further contribute towards the experimental validation of the proposed predictive models.

What we seek

A PhD candidate with the following required and preferred qualifications:

Required:

• Strong basis in molecular biology and biomedical sciences, as well as in bioinformatics;

• A project and result-oriented way of working with a planned approach;

• Team spirit to work in a multidisciplinary team of molecular biologists, toxicologists, bioinformaticians and computer scientists;

• Proof of excellence and ambition.

Preferred:

• Experience with ‘omics techniques (next-generation sequencing);

• Experience with cell technology;

• Strong self-motivation and drive;

• Fluency in English.

Fixed-term contract: 4 years.

The terms of employment of Maastricht University are set out in the Collective Labour Agreement of Dutch Universities (CAO). Furthermore, local UM provisions also apply. For more information look at the website www.maastrichtuniversity.nl.

Temporary employment for the period of max 4 years. Monthly salary is € 2.222,- gross/ month in year 1 up to € 2.840,-  in year 4.

Maastricht University is renowned for its unique, innovative, problem-based learning system, which is characterized by a small-scale and student-oriented approach. Research at UM is characterized by a multidisciplinary and thematic approach, and is concentrated in research institutes and schools. Maastricht University has around 16,300 students and 4,300 employees. Reflecting the university's strong international profile, a fair amount of both students and staff are from abroad. The university hosts 6 faculties: Faculty of Health, Medicine and Life Sciences, Faculty of Law, School of Business and Economics, Faculty of Humanities and Sciences, Faculty of Arts and Social Sciences, Faculty of Psychology and Neuroscience.

http://www.maastrichtuniversity.nl/

GROW - School for Oncology and Developmental Biology

GROW focuses on research and teaching of (epi)genetic, cellular and (micro)environmental factors and mechanisms underlying normal (embryonic and fetal) and abnormal (cancer) development, with emphasis on translational research aiming at innovative approaches for individualizing prevention, patient diagnostics and treatment.

http://www.grow-um.nl/