Within the scope of the ZonMw Translational Adult Stem cell program, a four year PhD-position is available within the Department of Biomaterials (Radboudumc, Nijmegen), headed by Prof. John A. Jansen. The collaborative project ‘ioCOMPONENTS’ will be carried out in close collaboration with DSM Biomedical and is focused on the use of autologous (= patient-own) components to aid in the regeneration and/or augmentation of bone tissue in an intra-operative setting. This translationally challenging project has the following targeted tasks:

• Develop a biobank for ADMSCs and SVF from donor-matched individuals;
• Compare osteogenic differentiation of ADMSCs and SVF from donor-matched individuals;
• Deliver proof-of-concept for SVF-based constructs toward bone regeneration/augmentation.

 
As a postdoctoral researcher, you will disseminate the obtained knowledge by scientific publications and presentations at (inter)national conferences. The preparation of grant proposals for personal funding might be encouraged (if progress is fruitful).

• MSc-degree in a relevant area: Medical Biology, Cell Biology, Biomedical Sciences, Biomedical Engineering;
• PhD-degree (or expected within max. 6 months);
• Highly experienced with cell culture techniques;
• Experience with relevant analytical techniques (biochemical assays, ELISA, etc.);
• Art. 9 certificate (WOD; related to pre-clinical studies with laboratory animals);
• A proven research track record;
• Collaborative mentality and team spirit;
• Independent and pro-active attitude.

Fixed-term contract: 1 year.

Scale 11: max € 68622 gross per year at full employment (incl. vacation bonus and end of year payments)

Radboudumc (university medical center)

Radboudumc strives to be a leading developer of sustainable, innovative and affordable healthcare to improve the health and wellbeing of people and society in the Netherlands and beyond. This is the core of our mission: To have a significant impact on healthcare. To get a better picture of what this entails, check out our strategy film.

Our key strength is medical life-sciences and clinical practice, with an impressive infrastructure comprising state-of-the-art technology platforms and (translational) research facilities. The Radboudumc is therefore uniquely positioned in the emerging Euregio and Dutch healthcare infrastructure to play a leading role in the new healthcare paradigm of prediction, prevention and personalised medicine.

The Radboudumc focuses on scientific health challenges of today, with an eye on emerging diseases of the future.

Read more about what it means to work at Radboudumc and how you can do your part.

https://www.radboudumc.nl/EN/Pages/default.aspx

The Department of Biomaterials is a leading multidisciplinary research group that focuses on developing bio-inspired strategies for the design of novel biomaterials and therapies for bone regenerative medicine. By studying the self healing capacity of natural tissues, fundamental insight in tissue regeneration is obtained. These insights are being implemented with the help of (synthetic) biomaterials, (autologous) cells, and signaling factors to orchestrate bone tissue regeneration. Currently, 21 PhD candidates, 6 post-docs, and a number of international visiting researchers are working enthusiastically on different topics of bone regeneration from a material, biological, medical, and dental perspective.