The human microbiome plays an important role in cancers of the intestinal tract, such as colorectal, pancreatic, gastric, and esophageal cancers. However, still little is known about the role of the microbiome in people with a genetic predisposition for colorectal cancer such as patients with the Lynch syndrome. Increasingly available ‘omics and meta’omics data now allows us to study these interactions at an unprecedented resolution.

At Radboud University Medical Center (Radboudumc), we have unique access to rare patient cohorts including people with genetic predisposition for cancer, as well as biobanks, and public and proprietary databases of patient- and microbiome data. We exploit these resources to study the molecular mechanisms of disease and contribute to personalized healthcare and therapeutics.
 
We invite applications for a postdoctoral position to investigate the role of the human microbiome in intestinal tract cancers. You will be positioned within the Centre for Molecular and Biomolecular Informatics (CMBI), while working in close collaboration with clinicians and researchers who have access to the samples from our hospital. “Tumors of the Digestive Tract” is a Radboudumc Core Research Theme that integrates members from different departments. Thus, you will be part of a cross-disciplinary research team striving to do world-class science and answer questions about the role of the human microbiome in health and disease.

You are an ambitious, self-motivated, and creative postdoctoral researcher with the following qualifications: 
 

• PhD degree in Biomedical Sciences, (Medical) Biology, Medicine, or a relevant other discipline;
• Experience in bioinformatics and/or computational analysis of metagenome data is essential;
• Strong motivation to succeed in scientific research;
• Interest in cancer pathogenesis and the interaction between the microbiome and the human host;
• Independent and well-structured style, demanding high quality of your own work;
• Speak and write English fluently;
• Self-motivated and good communicative skills;
• You recognise yourself in the Radboud way of working.

Fixed-term contract: 2 years.

Upon commencement of employment we require a certificate of conduct (Verklaring Omtrent het Gedrag, VOG) and there will be a screening based on the provided CV. Radboud university medical center’s HR Department will apply for this certificate on your behalf.

Read more about the Radboudumc employment conditions.

Scale 10: max € 58838 gross per year at full employment (incl. vacation bonus and end of year payments)

Radboudumc (university medical center)

Radboudumc strives to be a leading developer of sustainable, innovative and affordable healthcare to improve the health and wellbeing of people and society in the Netherlands and beyond. This is the core of our mission: To have a significant impact on healthcare. To get a better picture of what this entails, check out our strategy film.

Our key strength is medical life-sciences and clinical practice, with an impressive infrastructure comprising state-of-the-art technology platforms and (translational) research facilities. The Radboudumc is therefore uniquely positioned in the emerging Euregio and Dutch healthcare infrastructure to play a leading role in the new healthcare paradigm of prediction, prevention and personalised medicine.

The Radboudumc focuses on scientific health challenges of today, with an eye on emerging diseases of the future.

Read more about what it means to work at radboudumc and how you can do your part.

https://www.radboudumc.nl/EN/Pages/default.aspx

You will join the multidisciplinary team of Dr. Annemarie Boleij (molecular biologist/microbiologist) and Dr. Bas E. Dutilh (metagenomics) studying the involvement of the microbiome in intestinal cancers. You will work at the Centre for Molecular and Biomolecular Informatics (CMBI) (Prof. Dr. Martijn A. Huijnen) and collaborate with the departments of Pathology (Prof. Dr. Iris Nagtegaal) and Human Genetics (Prof. Dr Nicoline Hoogerbrugge).