Postdoc: Smart Nanoscopy of Biological Tissues

Postdoc: Smart Nanoscopy of Biological Tissues

Published Deadline Location
1 Aug 31 Aug Delft

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Job description

Do you want to be a part of a rapidly growing super-resolution lab, recently awarded with two major grants from the Dutch Netherlands Organisation for Scientific Research? Are you interested in working on the interface between physics, engineering and biology, to solve real-life problems and build advanced technological systems that can be used by researchers worldwide?


Advanced imaging methods such as multi-photon excitation microscopy provide 3-D imaging in biological tissues. If you like tinkering with hardware or the coding of fast computational algorithms to incorporate and extract information from large imaging datasets, then a PhD in super resolution microscopy is just wat you are looking for. The interdisciplinary projects concern the design and realization of a high-speed sensor, an adaptive optics module, and the software for aberration sensing and deformable mirror control.

Position: high-speed adaptive optics systems in super-resolution microscopy.

About us:

The aim of our research group is to increase microscopy robustness and resolution to nanoscopy-scale so that we can image intact live tissue. We believe that the time is right, both technically and conceptually, to make the step from optical microscopy to optical nanoscopy. We break away from the traditional design philosophy of mere addition of optimal components into a system, to instead apply optimal information processing for all components present in the system. The synergy between integrated optics and information processing allows us to develop completely new nanoscopy methodologies. During the next few years we will develop new optical methodologies in close collaboration with neuro-scientists who apply them. For us, it's all about creating new innovative methodologies that truly enable leading scientists to discover more about cellular functions and the neural network. That includes making our nanoscopy accessible, easier to use and more automated through smart hardware and data analysis tools. The field of smart optics systems is characterized using deformable mirrors, lenses and wavefront sensors and intelligent image processing to enhance the image quality in real-time of scientific observation equipment. Together with our collaborators we will set out to study the live brain with the aim to shed new nanoscale-light on the properties of the nervous system, e.g. the molecular plasticity associated with learning and memory-formation processes.


Delft University of Technology (TU Delft)


We are looking for candidates with a research profile that complements and/or expands our current activities.

Required qualifications and experience:

  • A PhD degree or equivalent degree preferably in physics, computer science or control.
  • Able to gather and analyse data effectively from different resources to build an eloquent, comprehensible and convincing story
  • Able to manage your time
  • Wide-ranging interdisciplinary interests


  • Focused and organised
  • Strong interpersonal and communication skills
  • Curiosity
  • Demonstrated ability to apply creativity and out-of-the-box thinking to produce innovative concepts and solutions

Conditions of employment

Fixed-term contract: 2 years.

The TU Delft offers a customisable compensation package, a discount for health insurance and sport memberships, and a monthly work costs contribution. Flexible work schedules can be arranged. Coming to Delft Service organizes diverse events for new international employees and their accompanying partners, like Partner Career Workshops and Dutch Culture Workshops. Located on campus are the International Children’s Centre and an international primary school which are subject to availability as well as several bilingual schools in the nearby surrounding. Salary and benefits are in accordance with the Collective Labour Agreement for Dutch Universities.


Technische Universiteit Delft

Delft University of Technology (TU Delft) is a multifaceted institution offering education and carrying out research in the technical sciences at an internationally recognised level. Education, research and design are strongly oriented towards applicability. TU Delft develops technologies for future generations, focusing on sustainability, safety and economic vitality. At TU Delft you will work in an environment where technical sciences and society converge. TU Delft comprises eight faculties, unique laboratories, research institutes and schools.


Faculty Mechanical, Maritime and Materials Engineering

The department Delft Center for Systems and Control (DCSC) of the faculty Mechanical, Maritime and Materials Engineering, coordinates the education and research activities in systems and control at Delft University of Technology. The Centers' research mission is to conduct fundamental research in systems dynamics and control, involving dynamic modelling, advanced control theory, optimisation and signal analysis. The research is motivated by advanced technology development in physical imaging systems, renewable energy, robotics and transportation systems.

More information:


  • Postdoc
  • Natural sciences
  • max. 38 hours per week
  • €3389—€4274 per month
  • Doctorate
  • 3mE19-65


Delft University of Technology (TU Delft)

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Mekelweg 2, 2628 CD, Delft

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