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As a PhD candidate, your aim is to identify core post-transcriptional programmes that impact on gene expression variability and ultimately cellular function. You will work on identifying the physical parameters, as well as circuit architectures (i.e. feedback mechanisms) governing gene expression dynamics in mammalian cells. In the first few months you will familiarise yourself with the field and develop a more detailed project outline. Throughout the project, you will gain extensive proficiency in the most current cell-free biochemistry, single-molecule and live-cell microscopy, and mathematical modelling techniques. You will communicate your findings through research articles during the course of your PhD. In addition to your research activities, you will be part of the educational programme of the Institute of Molecules and Materials, where you will develop various critical soft skills such as ethics, planning, and teaching. You will also develop your own scientific voice, as well as broaden and deepen your knowledge of the field of research by participating in symposia and conferences.
For recent work see: Cell, 2018, 173, 1609: Cell Syst., 2018, 7, 384; Nature Nanotech., 2016, 11, 191.
Fixed-term contract: You will be appointed for an initial period of 18 months, after which your performance will be evaluated. If the evaluation is positive, the contract will be extended by 2.5 years.
We want to get the best out of science, others and ourselves. Why? Because this is what the world around us desperately needs. Leading research and education make an indispensable contribution to a healthy, free world with equal opportunities for all. This is what unites the more than 22,000 students and 5,000 employees at Radboud University. And this requires even more talent and collaboration. You have a part to play!
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