We are looking for an enthousiastic PhD candidate for our project. The research task will mainly focus on the development of dosimetric methods for radionuclide therapy, and the development of mathematical models.

Tasks and responsiblities

• Performing dosimetric calculations and simulations based on microsphere distribution, radiation transport models, radiobiological models. Possibly, deep learning methods can help in identifying in common distribution pathways and solutions.
• Analyse scientific data.
• Write scientific publications and present findings at (inter)national scientific meetings.
• Work in a team with other scientists and clinicians to plan, discuss, and perform research in a stimulating environment.

• Master's degree in Medical Physics, Clinical technology, Technical medicine or equivalent with a focus on radio(nuclide) therapy physics.
• Demonstrated interest in solving complex modelling.
• Basic knowledge of dosimetry, mathematical modelling, treatment planning, radionuclide therapy, radiobiology and artificial intelligence.
• Permit to work with radioactivity (or willing to obtain this permit).
• Well-developed communicational and social skills directed towards working in a team.
• Enthusiastic and strong motivation to successfully complete a PhD.

Fixed-term contract: 3 years.

Upon commencement of employment we require a certificate of conduct (Verklaring Omtrent het Gedrag, VOG) and there will be, depending on the type of job, a screening based on the provided cv. Radboud university medical center's HR Department will apply for this certificate on your behalf.

Read more about the Radboudumc employment conditions and what our International Office can do for you when moving to the Netherlands.

Radboudumc

Department of Radiology, Nuclear Medicine and Anatomy
The department of Radiology, Nuclear Medicine and Anatomy is engaged in research on radionuclide therapies in different phases in development: from preclinical to standard clinically used nuclear therapies. The department is engaged in patient care, research and education in Radiology and Nuclear Medicine. Furthermore, there is good experience in artificial intelligence applications. The major expertise areas are Computed Tomography (CT), Magnetic Resonance Imaging (MRI) and nuclear medicine including both diagnostics and therapy. Dosimetry and health aspects are of central importance in all of these areas.

One of the important research areas is local nuclear interventions with radioactive holmium-166 micro- and nano-particles. These particles can be quantified in patients through SPECT, MRI and CT imaging. As MRI and CT provides a higher imaging resolution and SPECT has a higher sensitivity, the research will focus on optimized patient specific therapy in relation to dose-response for all three imaging modalities. Dosimetry models are of importance to get a better understanding of underlying mechanism in induced effects both at a small scale as at organ level.

The Local Nuclear Interventions group aims at the development of local image guided, personalized, adaptive radionuclide therapy, where the treatment is planned and delivered based on continuous dosimetric and dose-response assessments. With this goal we strive to optimize the clinical processes for multi-modality imaging and active motion management, introducing at best real-time dosimetric methods for treatment planning in the clinic. High precision delivery is obtained with its verification in space and over time, and advancing our radiobiological understanding to enable accurate modelling and prediction of the response of target and risk organs.

Research Institutes
At the moment there are more than 1,300 PhD candidates at our medical hospital. This number includes PhD candidates on our pay roll as well as external candidates (those employed somewhere else but researching on our premises).

• Radboud Institute for Health Sciences: ± 700
• Radboud Institute for Molecular Life Sciences: ± 400
• Donders Center for Medical Neurosciences: ± 200

Read what it is like to do a PhD at the Radboud University Medical Center.

Radboudumc
Radboudumc strives to be a leading developer of sustainable, innovative and affordable healthcare to improve the health and wellbeing of people and society in the Netherlands and beyond. This is the core of our mission: To have a significant impact on healthcare. To get a better picture of what this entails, check out our strategy.

Read more about what it means to work at Radboudumc and how you can do your part.