The group of Prof. dr. Geert Kops currently has a vacancy for a Postdoc to work on the role of chromosomal instability in cancer.

Description of the project:
Approximately 70% of all human tumors are aneuploid, which strongly correlates with tumor grade, metastasis and poor patient prognosis. One of the possible causes for aneuploidy is chromosomal instability (CIN): frequent gains and losses of whole chromosomes during cell division. We have recently shown that CIN can be highly oncogenic, depending on the severity of CIN and on the affected tissue. The underlying mechanisms are however still unknown. The candidate will work on a KWF-funded project (granted to and supervised by Dr. Nannette Jelluma) in which a mouse model of CIN is used to investigate the mechanisms underlying the oncogenic properties of CIN in intestinal cancer.

We are looking for a Postdoc who is highly motivated, flexible and works well both independently and in a team. The candidate should have a PhD degree and a strong interest in cancer biology. The candidate should be experienced in working with rodents, and is preferably Art. 9 certified. A proven publication track record is a must. Written and oral fluency in English is essential.

According to “CAO-Nederlandse Universiteiten” (CAO-NU), depending on experience scale 10 excluding 8% holiday allowance and an 8,3% year-end bonus. We offer an extensive package of fringe benefits.

Hubrecht Institute

The Hubrecht Institute is a research institute focusing on developmental and stem cell biology. It encompasses 24 research groups that perform fundamental and multidisciplinary research, both in healthy systems and disease models. The Hubrecht Institute is a research institute of the Royal Netherlands Academy of Arts and Sciences (KNAW)., located on the Utrecht Science Park ‘De Uithof’. Since 2008, the institute has been affiliated with the University Medical Center Utrecht, advancing the translation of research into clinical practice. The Hubrecht Institute has a partnership with the European Molecular Biology Laboratory (EMBL).