In a multidisciplinary collaboration with the Institute for Chemical Immunology (Leiden University) the axonal signalling group at the NIN has an exciting opportunity for a PhD student position in neuron-microglia physiology.
Microglia are immune cells that form the first line of defence and involved in development and disease of the central nervous system. To obtain a deeper understanding how microglia impact neurons this project examines the fundamental interactions between pyramidal neurons and microglia, using electrophysiology and two-photon microscopy infrastructure. We will combine electrophysiology, the next generation photochemical ligands, and take advantage of novel transgenic mouse lines to determine the bidirectional functional interactions ex vivo, both at the single-cell and sub-cellular level in neocortical grey matter (see e.g. Battefeld et al, Nat Commun 7:11298, 2016 and Cohen et al., Cell 180:311–322.e315, 2020).
We expect from you
You are a highly motivated, self-driven candidate. You hold a MSc degree in the field of neurosciences, physiology or another relevant discipline (e.g. immunology) and a strong interest for neuron-glia interactions. Experience with cellular research and/or microscopy is a major advantage. You furthermore possess a demonstrated proficiency in written and spoken English, possess excellent communication skills, creativity and flexibility. An ideal candidate is a team worker.
You should expect from us:
The position comes with an attractive package of fringe benefits and is for a period of 4 years in total. The first appointment is for 1 year with the option for an extension for the remaining period pending on an evaluation.
The salary and benefits will be commensurate with experience and institutional guidelines based on the Collective Labour Agreement for Dutch Universities; CAO NU). Full-time monthly salary for a PhD student is € 2.395 in the 1st year to € 3.061 in the 4th year before taxes. In addition, an 8% holiday allowance and an 8.3% year-end bonus are provided. We offer travel expenses, paid parental leave, flexible working hours, 30 days paid leave per year and assistance in finding an accommodation.
The position is immediately available and the deadline for applications is 12 July 2021.
The Netherlands Institute for Neuroscience is an Academy research institute. It conducts basic and strategic research in the neurosciences. It examines how the human brain makes awareness, perception, movement, learning, social interaction and other cognitive functions possible. It also studies how brain disorders can disrupt these functions.
The project is within the Axonal Signalling group of Prof. dr. Maarten H. P. Kole and based at the Netherlands Institute for Neuroscience (www.nin.nl). The NIN is the country’s leading fundamental neuroscience research institute, in the international and progressive city of Amsterdam. The institute provides a critical mass of scientists (spanning more than 27 nationalities) and neuroscience facilities, in a highly interactive, dynamic, multi-cultural environment, with English as the primary working language. The project is part of a multidisciplinary collaboration with the Institute for Chemical Immunology (ICI, https://chemicalimmunology.nl/) and the Amsterdam Neuroscience & MS Centre Amsterdam, Location VUmc, and funded by the Netherlands Research Organisation (NWO).
Diversity & Inclusion
The KNAW considers a working environment in which everyone feels welcome and appreciated of great importance. A working environment in which attention is paid to individual quality and where development opportunities are paramount. Together we strive for an inclusive culture in which we embrace differences. We would therefore like to invite candidates who want to contribute to this through their background and experience. In the event of equal suitability, preference will be given to the candidate who thus enhances diversity within the Academy.
We will not respond to any supplier enquiries based on this job advertisement.
Royal Netherlands Academy of Arts and Sciences (KNAW)
Meibergdreef 47, 1105 BA, Amsterdam Zuid-Oost
Please send your application including:
Make sure to apply no later than 11 Jul 2021 23:59 (Europe/Amsterdam).
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