Open position for a research technician- Developing and performing bioassays to examine cell-biomaterial interactions, as part of Materials-Driven Regeneration (MDR) Gravitation program

Open position for a research technician- Developing and performing bioassays to examine cell-biomaterial interactions, as part of Materials-Driven Regeneration (MDR) Gravitation program

Published Deadline Location
28 Jun 21 Jul Maastricht

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Department of Instructive Biomaterials Engineering (IBE), MERLN Institute for Technology-Inspired Regenerative Medicine, Maastricht University

Job description

At the MERLN Institute for Technology-Inspired Regenerative Medicine of Maastricht University, Department of Instructive Biomaterials Engineering (IBE), we currently have a vacancy for a research technician on “Developing and performing biological assays to examine cell-biomaterial interactions” as part of the Materials-Driven Regeneration (MDR) program. We are looking for a technician with knowledge and expertise in human cell culture, and cell- and molecular biology assays such as RT-qPCR, ELISA, Western blot, immunohistochemistry and related imaging techniques.

Development of new regenerative therapies for damaged and diseased tissues and organs, such as complex cellular assemblies from intelligent biomaterials is dependent on availability of advanced biological models combined with reliable and accurate biological assays. Such assays provide in-depth knowledge of safety and efficacy of the therapies and the underlying biological mechanisms including the intricate and interrelated cell-cell and cell-biomaterial interactions.

In this position, the research technician is expected to assist in and supervise various research projects aimed at developing advanced regenerative therapies and make an important contribution to the advancement of our research goals. The work will predominantly be focused on (1) performing two- and three-dimensional (2D and 3D) in vitro cultures of cells, alone or together with biomaterials, (2) developing and performing analyses based on molecular biology assays and imaging techniques on the cultured cells/tissues, (3) optimizing and writing relevant protocols, and (4) contributing to organizational tasks in the labs. The research technician will be embedded in the Department of Instructive Biomaterials Engineering (IBE) at the MERLN Institute for Technology-Inspired Regenerative Medicine. The research at MERLN (https://merlninstitute.com/) is focused on developing novel and breakthrough technologies to advance the field of repair and regeneration of functional tissues and organs. The research at IBE department (https://merlninstitute.com/discover-merln/departments-and-groups/ibe-department) focuses on the development of regenerative therapies based on smart biomaterials and their complexes with cells and molecular cues, and on micro- and nanotechnology tools for regenerative medicine.

Specifications

Maastricht University (UM)

Requirements

You should have a bachelor or a master degree in biology, molecular biology or biomedicine. Candidates from related disciplines such as biomedical engineering, bioengineering, biomaterials, etc. with ample experience in using molecular biology and cell culture techniques are also welcome to apply. Hands-on experience (e.g. through previous job experiences, a master thesis or an internship) in the following is required:

  • Molecular biology techniques such as mRNA extraction and cDNA synthesis, q-PCR, protein analysis through Western blot, ELISA and protein multiplex analysis, immunocytochemical and immunohistochemical analyses;
  • Imaging techniques;
  • Cell culture techniques including the culture and maintenance of different human cells (experience in culturing stem cells or induced pluripotent stem cells is preferred);
  • Being familiar with cell differentiation protocols as well as 3D cell or organoid culture is a plus;
  • Development and optimization of assays and writing of protocols;
  • Experience with analysis of cell-biomaterial interactions is a plus;
  • Good command of scientific English in terms of listening, speaking, reading and writing is required.

We offer a collaborative position embedded into a highly interdisciplinary and international institute, which is one of the worldwide leading research institutions in the tissue regeneration field. Our modern laboratories include labs for materials synthesis and characterization, biofabrication/-printing, (clean room) micro-/nanofabrication, microfluidics, cell culture, histology, molecular biology, imaging/microscopy, all provided with latest-state-of-the-art equipment.

Conditions of employment

Fixed-term contract: 1 year, with the possibility of extension for 1 year after a positive evaluation.

We offer a full-time temporary contract for a period of 2 years (initially 1 year, which will be extended for another 1 year after a positive evaluation at the end of the first year).

Depending on experience and qualification, the maximum gross monthly salary is € 3.548,- (on a full-time basis) in accordance with scale 7 or 8. On top of this, we offer an 8% holiday and an 8.3% year-end allowance. Furthermore, local UM provisions also apply.

The terms of employment of Maastricht University are set out in the Collective Labour Agreement of Dutch Universities (CAO). Furthermore, local UM provisions also apply. For more information look at the website www.maastrichtuniversity.nl > Support > UM employees.

Employer

Maastricht University

Maastricht University is renowned for its unique, innovative, problem-based learning system, which is characterized by a small-scale and student-oriented approach. Research at UM is characterized by a multidisciplinary and thematic approach, and is concentrated in research institutes and schools. Maastricht University has around 20,000 students and 4,700 employees. Reflecting the university's strong international profile, a fair amount of both students and staff are from abroad. The university hosts 6 faculties: Faculty of Health, Medicine and Life Sciences, Faculty of Law, School of Business and Economics, Faculty of Science and Engineering, Faculty of Arts and Social Sciences, Faculty of Psychology and Neuroscience. For more information, visit www.maastrichtuniversity.nl.

Department

About MDR program:

The Research Center for MDR (https://mdrresearch.nl/) is a partnership between Eindhoven University of Technology, Maastricht University and Utrecht University, University Medical Center Utrecht and the Hubrecht Institute. This consortium was brought together to advance tissue and organ regeneration approaches with the use of instructive biomaterials and funded by the ministry of education, culture and science of The Netherlands in the framework of the Gravitation program. The interdisciplinary team of researchers within the MDR consortium aims to focus on the research and development of new, intelligent materials that stimulate the regeneration of damaged or diseased tissues and organs.

Specifications

  • Technical and laboratory
  • max. 38 hours per week
  • €2329—€3144 per month
  • AT2021.260

Employer

Maastricht University (UM)

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Location

Universiteitssingel 40, 6229 GR, Maastricht

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