Your daily work will include cell and (3D) tissue culture, biochemistry, molecular biology, tissue engineering, and bioreactor technology. Additionally you will apply the organoid models for ADME testing of chemicals and medicines, and develop new QIVIVE approaches.   The project will be supervised by the several work package leaders of the RAAK-PRO grant (Professor Ronette Gehring, Dr Marije Strikwold ERT and Dr Bart Spee). The project is directed on generating organoid cultures from various tissues of cows for advanced in vitro modelling. For this purpose we will use adult stem cell cultures (organoids) and bioreactor technology approaches. The first two years will be conducted in Utrecht, whereas the last two years will be at the VHL facilities at Leeuwarden.

We are looking for a Master student with a degree in Biomedical Sciences; who preferentially has recently participated in organoid-related studies and has experience with advanced in vitro models and/or kinetic modelling. Experience in programming software and organoid culture is a big advantage for the successful imbedding of the PhD-student. 

The current job opportunity is supported by a consortium grant including academic and private institutes and will be conducted at the Department of Clinical Sciences (CS) as well as Van Hall Larenstein University of Applied Sciences (VHL) and participates within the theme of Regenerative Medicine; one of the focus points of Utrecht Life Sciences. The CS group focuses on Tissue Engineering using organoid technology whereas VHL has expertise in in vitro ADME assays and kinetic modelling, including Quantitative In Vitro to In Vivo Extrapolation (QIVIVE). Within the RAAK-PRO project we will develop organoid based in vitro models of tissues from cows related to food safety.

We offer a temporary position (1.0 FTE) for a period of one year. After a positive evaluation, the appointment will be extended with three years. The gross salary starts with € 2,541 per month in the first year and increases to €3,247 per month in the fourth year of employment (scale P according to the Collective Labour Agreement Dutch Universities) per month for a full-time employment. Salaries are supplemented with a holiday bonus of 8% and a year-end bonus of 8.3% per year. 
In addition, Utrecht University offers excellent secondary conditions, including an attractive retirement scheme, (partly paid) parental leave and flexible employment conditions (multiple choice model). For more information, please visit working at Utrecht University.

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