Postdoc researcher Immunology

Postdoc researcher Immunology

Published Deadline Location
3 Aug 24 Aug Amsterdam
We are looking for a motivated Postdoc to join our dynamic team, who is ready for an opportunity to perform cutting-edge research and contribute to the fight against cancer.

Job description

The project

The Postdoc will be responsible for the design, production and functional testing of intracellularly expressed antibodies, formulated as mRNA transfection vehicles and targeted at oncogenic signaling pathways involved in immune suppression or at spliceosome constituents. Ultimate aim is to enhance the immunogenicity of cancer and so support immunotherapy approaches.

The project is part of a research consortium, funded by the European Union Research and Innovation Actions: HORIZON-HLTH-2021-TOOL-06-02. The CANCERNA consortium brings together molecular biologists and immunologists from six countries in a concerted effort to exploit mRNA-based approaches and mRNA processing modulation in cancer immunotherapy.

About your role

Your main tasks and responsibilities are:

  • To screen for, identify, and clone genes encoding targeted antibody fragments;
  • To set up and operationalize in-vitro transcription of antibody mRNAs;
  • To set up mRNA-based transfection protocols for intracellular antibody expression in tumor cells;
  • To carry out flowcytometric, transcriptional, and functional profiling of intracellular antibody-modulated tumor; cells and study their effects on immune effector cells;
  • To analyze and write reports and papers on the obtained data.

Specifications

Academic Medical Center (AMC)

Requirements

About you

We are looking for a highly motivated and enthusiastic postdoc:

  • With a PhD degree in Biomedical Sciences or Biochemistry and with affinity for Immunology;
  • With experience with molecular biology techniques, specifically in-vitro mRNA transcription and transfection;
  • You have a flexible, pro-active team spirit but you can also work independently;
  • You have excellent communication skills in English, both written and verbal.

Conditions of employment

Fixed-term contract: 3 years.

Our offer

  • The intended start date for the project is ASAP. We offer a fixed term contract for 3 years.
  • Besides a good basic salary, you will also receive an 8.3% year-end bonus and 8% holiday allowance. Calculate your net salary here.
  • Free and unlimited access to our online learning environment GoodHabitz.
  • Pension accrual with ABP, of which we pay 70% of the premium.
  • Reimbursement of 75% of your public transport costs. Would you rather travel by bike? Then we have a good bicycle scheme.
  • An active personnel association and the Young Amsterdam UMC association, both of which organise fun (sports) activities and events.
  • For an overview of all our other terms of employment, see https://werkenbij.amsterdamumc.org/

Bekijk alle arbeidsvoorwaarden van Amsterdam UMC

What to expect

  • A job in our beautiful capital city
  • Working for the favorite employer in healthcare (intermediary 2021)
  • All colleagues have the same goal: contributing to tomorrow’s care
  • There is room for development, deepening and broadening of your knowledge
  • An active staff association that organizes fun activities and arranges discounts on products and services for you
  • Amsterdam UMC innovates continuously, which requires a flexible attitude from everyone
  • Two large locations, good for your pedometer!
  • You have more than 15.000 colleagues, not all of whom you will get to know personally

Employer

Amsterdam UMC

About your workplace

As Potsdoc researcher you will be working at the Amsterdam UMC (location VUmc) in the Immunotherapy Lab of the Cancer Center Amsterdam (CCA) under supervision of Prof Tanja de Gruijl and Prof Hans van der Vliet.

Research within the CCA Immunotherapy Lab is performed in a stimulating environment and at an international highly competitive level. You will be part of a highly motivated team of (pre-) clinical researchers. The focus of research is on the tumor microenvironment and cancer immunotherapy.

Amsterdam UMC has an open culture. This means that we hope that everyone feels welcome in our organization and that we strive to offer equal opportunities to everyone. We therefore cordially invite all interested parties to respond to this vacancy. Check out our approach to diversity and inclusion.

Meet your colleagues. Watch video’s of your future colleagues:

Additional information

Let’s meet!

You can contact Prof. Dr. Tanja de Gruijl or Prof. Dr. Hans van der Vliet via e-mail td.degruijl@amsterdamumc.nl or jj.vandervliet@amsterdamumc.nl, or by telephone +31 20 4445152.

If you need more information about the application procedure, contact Tanja Hart, corporate recruiter at 020-4445635.

A reference check, screening and hiring test may be part of the procedure. Read hier whether this also applies to you. If you join us, we ask for a VOG (Certificate of Good Conduct). Foreign citizens need to provide comparable police clearing certificates.

Acquisition in response to this vacancy is not appreciated.

Specifications

  • Postdoc; Research, development, innovation
  • Health; Natural sciences
  • max. 36 hours per week
  • €3047—€4800 per month
  • Doctorate
  • SP AU 20220803

Employer

Academic Medical Center (AMC)

Learn more about this employer

Location

De Boelelaan 1117, 1081 HV, Amsterdam

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Application procedure

A reference check, screening and hiring test may be part of the procedure. Read hier whether this also applies to you. If you join us, we ask for a VOG (Certificate of Good Conduct). Foreign citizens need to provide comparable police clearing certificates.

Acquisition in response to this vacancy is not appreciated.

Application procedure

Application procedure

A reference check, screening and hiring test may be part of the procedure. Read hier whether this also applies to you. If you join us, we ask for a VOG (Certificate of Good Conduct). Foreign citizens need to provide comparable police clearing certificates.

Acquisition in response to this vacancy is not appreciated.

Make sure to apply no later than 24 Aug 2022 23:58 (Europe/Amsterdam).