We are offering a 3.5-year full-time (0.8 - 1.0 FTE) postdoctoral position. The Julius Center, University Medical Center Utrecht and the Leiden Academic Centre for Drug Research at Leiden University are looking for an enthusiastic and forward-thinking life scientist that is interested in integrating insights from cell biology, omics technologies, and systems biology into epidemiological studies of chemical exposure and adverse health effects using bioinformatics and statistical tools.
The human population is exposed to a vast number of chemical pollutants. It is estimated that of the over 140,000 approved chemicals, 5000 lead to significant exposure levels in the human population. Many of these chemicals, let along their combination, have not been adequately tested. To better understand the toxicological footprint of these exposures integrated interdisciplinary approaches are needed. Combining inference from human molecular observational studies and in vitro
experiments through bioinformatics and statistical tools provides possibilities to improve chemical risk assessment.
This postdoctoral position embedded in the RISK-HUNT3R project (https://www.risk-hunt3r.eu/
). RISK-HUNT3R, short for "RISK assessment of chemicals integrating HUman centric Next generation Testing strategies promoting the 3Rs", is a European Research & Innovation project funded under the European Commission's Horizon 2020 programme. In this position you will work on developing, validating, and implementing integrated approaches to lead the way towards next-generation risk assessment (NGRA).
Your work will be on the interface of environmental epidemiology and in vitro
and in silico
mechanism-based approaches and will have the explicit ambition to integrate strategies for the assessment of chemical exposure, toxicokinetics, and toxicodynamics.
You will be supervised by Prof. R.C.H. Vermeulen
, Prof B. de Water
and Dr. Jelle Vlaanderen