At present, the availability of donor organs is desperately insufficient to meet the need. The availability of high-quality donor organs - needed for a successful transplantation - will be even further at risk due to ageing and lifestyle changes of the population. Namely, organs retrieved from elderly, obese or unhealthy lifestyle donors and those donated after cardiac arrest do not recover from injury inherent to surgery as completely as young organs. New strategies are needed to solve the donor organ shortage.
In the Flagship 'Organ Transplantation: making unsuitable donor organs suitable', Erasmus University Rotterdam, Erasmus Medical Centre and Technical University Delft join their research forces (https://convergence.nl/flagship-organ-transplantation/
). Technological innovations are envisioned to build a long‐term machine perfusion platform to not only sustain but also recover donor organ viability out‐of‐the‐body. Hence, damaged donor organs will be made suitable for transplantation.Job description
This vacancy is for a PhD candidate who will principally focus on costs, effects, economic evaluation and health technology assessment research to determine the economic and societal consequences of new strategies to organ transplantation (kidney, liver, heart, and lung). Through all aspects of the research program, the technologically innovative strategy for organ transplantation will raise important societal questions about prioritization, health‐related quality of life, well‐being, and cost‐effectiveness issues. The PhD candidate job position will (1) determine the short‐ and long‐term effects of using repaired organs vs other alternatives on physical and mental health outcomes, quality of life (QoL), and societal and healthcare costs; (2) determine the effects of extra donor organ supply on waiting lists, the inclusion of new patient groups, societal and individual health outcomes, QoL and costs, depending on allocation mechanisms for different organs; (3) weigh the ethical, legal, clinical, economic, and patient preference aspects in an (early) Health Technology Assessment (HTA) concerning organ transplantation; and (4) be involved in generating tools to monitor the costs, (clinical) benefits and stakeholder preferences after organ transplantation. Besides research responsibilities, the PhD candidate will also participate in our teaching programs (up till 0.15fte).