In the context of the Sectorplan Medical Sciences, Radboudumc center is offering an exciting and varied associate professor position for a senior statistician with interest in methodology of clinical research and drug development. Will you join our ambitious team? Radboudumc aims to accelerate the development of rare disease therapies by filling the gap between preclinical and clinical science. The
Sectorplan Medical Sciences provides funding for 13 structural positions to foster research and education in this field.
The field of clinical research in rare diseases urgently needs experience in innovative study designs and methodology. Due to the small populations and wide variety in diseases addressed, this innovation is essential to clinically explore effects of new treatments and to adequately confirm their efficacy to support licensing and reimbursement. This for example is the case for drug repurposing but also for innovative medications as gene- and cell-based therapies (ATMPs) such that new treatments really reach our patients.
We are searching for a statistician who has experience in clinical trials and their designs, and is strongly motivated to further develop this interesting field. You will have an active engaging and facilitating approach to clinical research for rare diseases in Radboudumc and beyond. You also contribute to the learning community that we will form on drug development for rare diseases and collaborate within the clinical drug development team with two pharmacists, a trial coordinator and trial support.
As an associated professor, you will advance clinical trial methodology for clinical trials in small populations. Jointly with the clinical expert teams you will design, help execute and analyze clinical trials in e.g., rare cancers, rare neurological, rare neuromuscular, rare sensory and rare kidney disorders. You will further develop the methodology for trials in rare diseases and personalized medicine, e.g., in platform trials, novel endpoints and analyses and/or Bayesian approaches.
Given the context and advanced nature of the clinical research, you will engage in grant proposals for clinical projects as well as develop methodological proposals. You will engage in teaching at BSc, MSc and post-graduate level, ensuring that relevant new developments find their place there. This may include contributions to new master or post-graduate level courses. You will strengthen research collaborations within Radboudumc, based on the advanced methodological expertise gained.
As associate professor Innovative Clinical Trial Design you will:
- establish an overarching research line aiming at innovating and implementing methodology for clinical research in rare diseases, leveraging clinical trials, modelling and emerging real world data sources.
- contribute to implementing a master track in therapy development and to teaching in the area of therapy development at bachelor, master and post-graduate level.
- lead and further build a research group, providing guidance to scientists with a focus on teaching, postdocs and PhDs and students from the various curricula of the Radboud(umc).
- actively collaborate with Radboudumc researchers on therapy development for rare disorders.
- acquire external competitive funding.
- be part of Radboudumc and (inter-)national research consortia on therapy development for rare diseases.
- contribute to policy making in rare disease therapy development.