Your work environment

The research is headed by dr. Thijssen and is embedded in the Angiogenesis Laboratory Amsterdam of the department of Medical Oncology. The project is a close collaboration with the immunotherapy group headed by prof. De Gruijl.

An adequate anti-tumor immune response relies on different external cues that guide and activate the appropriate immune cells. Galectins and cytokines are proteins involved in these immunomodulatory cues. We have found that galectins and cytokines can directly interact which affects their function. The current project aims to provide proof-of-concept that these interactions can shape the anti-tumor immune response.

Your challenge

Using molecular and cellular techniques the effects of the interactions will be studied with regard to protein function (glycan binding) as well as cellular function (immune cell survival/activation/differentiation). You will be responsible for managing the project and performing experiments together with a technician.

The project is funded by the Dutch Cancer Society. You are involved in obtaining additional funding to continue the project for four years.

We are looking for an enthousiastic postdoc with experience in (molecular) cell biology, flow cytometry and immunology that preferentially has affinity/experience with glycobiology and protein work.

Salary Scale 10: 2659 tot 4216 euro gross when employed full-time (depending on qualifications and experience).

In addition to a good monthly salary we offer, among others, 8,3% extra allowance at the end of the year and 8% for holidays. For more information on our conditions, please visit www.werkenbijvumc.nl/arbeidsvoorwaarden (Dutch version with link to English collective labor agreement).

For Dutch citizens it is mandatory to provide a VOG (Verklaring Omtrent Gedrag).