We have a vacancy for a talented and enthusiastic PhD student to join our team at the Academic Medical Center in Amsterdam. Our ambitious team conducts cutting edge research in cardiac arrhythmias that cause sudden cardiac death. Our projects are multidisciplinary and translational, spanning clinical cardiology, clinical genetics, molecular genetics, biostatistics and disease modeling in cellular systems and mice. We are an internationally oriented group and have multiple ongoing collaborations with research groups in Europe, the USA and Asia.

The successful candidate will conduct mechanistic studies on genes that have been linked to cardiac electrophysiology or arrhythmia through genetic studies that have been conducted within our group. The candidate will study these genes within a team of molecular biologists and electrophysiologists to decipher the mechanisms by which they modulate cardiac electrophysiology and arrhythmia risk. Studies will be conducted in state-of-the-art experimental model systems that include (CRISPR/Cas) genetically modified mice and iPSC-CMs (induced pluripotent stem cell derived cardiomyocytes).

• You have an MSc degree in Medicine, Medical Biology or Biomedical Sciences.
• You are preferably proficient in statistical programming languages and statistical analysis methods (eg. R)
• You are flexible and can handle different projects concurrently
• You are a team player that shares knowledge and skills with colleagues
• You are independent and have good organizational skills
• You have excellent written and verbal communication skills
• You are fluent in English (written and spoken)

We offer a fixed term contract for 36 hours per week for 1 year, starting preferably before or at September 2018, which under normal circumstances will be prolonged with 3 years. The salary is in accordance with the description of salary for a PhD student in the CAO-UMC.

 A PhD student (Onderzoeker in Opleiding) is placed in scale 21, with a fulltime gross salary that ranges from €2279,- to €2919,- (based on qualifications and experience).

 For a doctor (Arts-Onderzoeker) it’s scale 10, with a fulltime gross salary that ranges from €2919,- to €4216,- (based on qualifications and experience).

 The applicant will get a contract through the AMC Medical Research BV, which includes a payment of holiday allowance of 8% and a year-end bonus of 8.3% of the gross annual salary.

The AMC is more than just a hospital. It is a world in which patient care, research and education are integrated, and in which people are always central. It is an academic world full of possibilities for talented individuals that are looking for a place where they can excel. Thinking big, daring to dream, cooperating internationally. And never letting yourself be put off by ‘It’s not possible’ or ’It won’t work anyway’. That is the AMC mentality.

The department of Experimental Cardiology is a research laboratory consisting of 5 groups each led by a group leader / principal investigator. The department has a long-standing tradition of research on cardiac arrhythmias that cause sudden cardiac death. The department is an integral part of the ‘Hartcentrum’ of the AMC, which means that researchers are connected to the Clinical Cardiology department, which stimulates translational research that benefits patients suffering from life-threatening cardiac diseases.