Postdoc – neuroscience & bioinformatics (single cell long read RNAseq in neurodegeneration)

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Postdoc – neuroscience & bioinformatics (single cell long read RNAseq in neurodegeneration)

Two year postdoctoral position studying how cell specific isoforms contribute to amyotrophic lateral sclerosis (ALS).The work will combine advanced bioinformatics with single cell long read RNAseq of patient tissue + additional omics datasets.

Deadline Published Vacancy ID 2025-6486
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11 days remaining

Academic fields

Health

Job types

Postdoc

Education level

Doctorate

Weekly hours

36 hours per week

Salary indication

€3598—€5669 per month

Location

Heidelberglaan 100, 3584CX, Utrecht

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Job description

You will focus on analysing single cell long read RNAseq data generated by our team. You will work to discover cell specific isoforms and relate them to pathological signatures and genetic risk factors in ALS patient tissue. You will apply supervised and unsupervised machine learning methods using a local high performance computing cluster. You will work closely with experts in ALS, bioinformatics, neuroscience and RNA biology. You will support in the supervision of more junior researchers and students.

Requirements

You have a PhD in bioinformatics, genomics or neuroscience with at least 1 first author publication. You are ambitious, have strong communication skills and are a good presenter / scientific writer. You enjoy being proactive and taking a leading role in your work. You can envisage providing mentorship to junior researchers / students. You can work both independently and as part of a team when needed. You have experience in advanced bioinformatic analyses of omics datasets, preferably single cell and/or long read RNAseq data.

Demonstrable experience in advanced machine learning and/or high performance computing is an advantage. Prior lab experience in genomics / tissue analyses is an advantage but not required(eg NGS library preparations, tissue sectioning, qPCR, smFISH).

For further details, please contact the project supervisor Dr Kevin Kenna (K.P.Kenna@umcutrecht.nl)

Conditions of employment

The maximum salary for this position (36 - 36 hours) is € 3.598,00 gross per month based on full-time employment.

In addition, we offer an annual benefit of 8.3%, holiday allowance, travel expenses and career opportunities. The terms of employment are in accordance with the Cao University Medical Centers (UMC).

Department

You will work in the department of translational neuroscience at the UMC Utrecht. You will also function as a member of the Dutch ALS research center and the Utrecht Bioinformatics Center.

Additional information

Contact our colleague:
Dr Kevin Kenna
+31 88 756 88 77
k.p.kenna@umcutrecht.nl

Werken bij UMC Utrecht

Werken in het UMC Utrecht betekent werken op het snijvlak van onderzoek, onderwijs, zorg en techniek. In onze academische setting leren en innoveren we continu en zijn nieuwe ontwikkelingen altijd binnen handbereik.

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