Postdoc Human ex vivo model to study nonalcoholic fatty liver disease (1.0 FTE)

Postdoc Human ex vivo model to study nonalcoholic fatty liver disease (1.0 FTE)

Published Deadline Location
10 Oct 24 Oct Groningen

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Job description
The Groningen Research Institute of Pharmacy (GRIP) in the Faculty of Science and Engineering (FSE) has a position for a postdoctoral fellow in the Pharmaceutical Technology and Biopharmacy group. We offer a challenging, interdisciplinary research project whose a

Job description

Job description
The Groningen Research Institute of Pharmacy (GRIP) in the Faculty of Science and Engineering (FSE) has a position for a postdoctoral fellow in the Pharmaceutical Technology and Biopharmacy group. We offer a challenging, interdisciplinary research project whose aim it is to develop a microfluidic biological model to study nonalcoholic fatty liver disease, termed Non-Alcoholic SteatoHepatitis (NASH). The objectives of the project are to (1) address the induction of steatosis in the liver utilizing an ex vivo precision-cut liver slice model, and (2) to develop a microfluidic device to study the effect of the effluent of nonalcoholic fatty liver precision-cut liver slices on human effector cells (e.g. fibroblasts and cancer cells), and (3) to identify NASH-specific biomarkers.

You will be working in a stimulating interdisciplinary biomedical team including cell biologists, analytical chemists, and medical clinicians. You will be involved in the supervision of PhD students. There will be close collaboration with the Pharmaceutical Analysis group in GRIP (Prof. Sabeth Verpoorte,Microfluidics) and with the University of Mainz (Prof. Detlef Schuppan, NASH).

Specifications

University of Groningen

Requirements

You have knowledge of, and research experience in, the biomedical sciences and/or cell biology as evidenced by a successful PhD research project with publications/conference presentations. Creative thinking, initiative, management skills and good verbal and written English proficiency are a necessity. Proficiency in the Dutch language would be an asset, as would be experience with culturing of precision-cut tissue slices. The ideal candidate is enthusiastic, ambitious, and a team player.

Conditions of employment

Fixed-term contract: 24 months.

We offer you in accordance with the Collective Labour Agreement for Dutch Universities:
• a salary of € 3.255 gross per month, up to a maximum of € 3,895 gross per month (salary scale 10)
• a full-time position, for two years (1.0 FTE)
• a holiday allowance of 8% gross annual income
• an 8.3% year-end bonus
• a personal budget of € 1,000 per year is dedicated for additional training and career activities.

The preferred starting date is 1 December 2019.

Department

Faculty of Science and Engineering

Since its foundation in 1614, the University of Groningen has enjoyed an international reputation as a dynamic and innovative centre of higher education offering high-quality teaching and research. Balanced study and career-development paths in a wide variety of disciplines encourage more than 31,000 students and researchers to realize their own potentials. We are truly an international place of knowledge, and belongs to the most prestigious research universities in Europe and the top 100 universities worldwide.

Specifications

  • Postdoc
  • Natural sciences
  • max. 38 hours per week
  • Doctorate
  • 219515

Employer

University of Groningen

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Location

Broerstraat 5, 9712 CP, Groningen

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