We are searching for a young scientist who is interested to use single molecule imaging and super-resolution microscopy to study trafficking and transport of proteins across epithelial barriers. The function is part of the EUROSTARS project g2B (Gut-to-Blood) of Dr. Lorenzo Albertazzi. The objective is to use advanced methods such PAINT super-resolution microscopy and single molecule tracking to acquire new knowledge on the receptor binding, intracellular trafficking and transcytosis of protein carriers across intestinal monolayers. In particular the use of protein constructs developed in the project to target cell receptors and promote transport will be explored. The project is embedded in a European consortium and will benefit of international collaborations with groups active in the field of targeting ligands, protein expression and in vivo biology.

About Eindhoven University of Technology (TU/e):
The TU/e is a University of Technology with a focus on Health, Energy and Mobility. Within the Health area, several departments cooperate on topics such as Chemical Biology, Regenerative Medicine, Computational Biology, and Biosensing, with close links to healthcare and industry. The TU/e is an open and inclusive university with short communication lines. The people are curious, collaborative, and strive for excellence. TU/e enables its academic staff to develop research and education at an internationally renowned level. Our lively campus community facilitates connections between staff and students, in an open, friendly, vibrant atmosphere that welcomes and inspires.

About the Department of Biomedical Engineering (BME):
The Department of Biomedical Engineering offers a research driven BME Bachelor program and Masters Biomedical Engineering, Medical Sciences and Technology and Medical Engineering in its Graduate Program. Research areas range from Molecular Bioengineering and Imaging, Biomechanics and Tissue Engineering to Biomedical Imaging and Modeling. The department has more than 800 students and up to 200 tenured and non-tenured employees.

About the Institute for Complex Molecular Systems (ICMS):
The Institute for Complex Molecular Systems is an interdisciplinary institute at Eindhoven University of Technology (TU/e) which brings excellent researchers from different areas together to promote cross-breeding of ideas across disciplines in the departments Biomedical Engineering, Applied Physics, Chemical Engineering and Chemistry, Mathematics and Computer Science, and Mechanical Engineering. The institute aims to create and study biologically relevant functional structures with the ultimate goal of understanding the complexity of life.

We are looking for enthusiastic candidates who have a PhD in Biophysics, Biomedical Engineering, cell/molecular biology or related topics. Experience with super-resolution and single molecule imaging, cell and tissue imaging and image analysis is an asset.

• A meaningful job in a dynamic and ambitious university with the possibility to present your work at international conferences.
• A full-time employment for 2 years.
• You will have free access to high-quality training programs on general skills, didactics and topics related to research and valorization.
• A gross monthly salary and benefits in accordance with the Collective Labor Agreement for Dutch Universities.
• A broad package of fringe benefits (including an excellent technical infrastructure, moving expenses, and savings schemes).
• Family-friendly initiatives are in place, such as an international spouse program, and excellent on-campus children day care and sports facilities.