We are looking for a postdoctoral candidate to develop novel serological immunoassays. These will include assays for measuring concentrations of therapeutic antibodies, and immunogenicity assays (including ELISAs and RIAs), and will be used both to support interdisciplinary clinical research aimed at optimizing the use of biopharmaceutical drugs, as well as implemented in the division of Sanquin Diagnostics as routine diagnostic tests. Results using novel assay from basic as well as clinical cohort studies will form the basis of future publications.

• PhD in biomedical or biopharmaceutical sciences;
• Experience with ELISA;
• Knowledge of antibodies;
• Experience with recombinant protein expression and purification is a pro;
• Interest in applied and translational science;
• Good command of written and spoken English;
• Ability to work independently as well as team player.

Fixed-term contract: 1 year with possible extension.

• Challenging project in a multi-disciplinary and enthusiastic team; 
• Salary and conditions are conform CAO Sanquin;
• Temporary position for the duration of one year with possible extension.

Sanquin

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Department of Immunopathology

The Immunoglobulin Research group is part of the Department of Immunopathology. We investigate structural and functional properties of antibodies with the aim of understanding their role in immunological processes as well as their therapeutic application. The department comprises 40-45 people (postdocs, PhD-students, undergraduate students and technicians) that all work on related research topics. 

We collaborate closely with the division Diagnostics, which offers a range of assays for immunogenicity testing and therapeutic drug monitoring of monoclonal therapeutics. Furthermore, we collaborate extensively with clinicians to investigate the pharmacokinetics and pharmacodynamics of monoclonal antibodies.