Postdoc position in single cell analysis of cell differentiation in vivo (1.0 FTE)

Postdoc position in single cell analysis of cell differentiation in vivo (1.0 FTE)

Published Deadline Location
29 Jun 31 Jul Utrecht

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Take part in an exciting team effort by world-leading scientists to decipher how individual cells acquire their specialized fate. Apply now!

Job description

The van den Heuvel lab currently offers a post-doctoral research position in Developmental Biology. The focus of the project will be to reveal the regulatory logic of cellular decision making in the context of animal development. Specifically, we seek to better understand how precursor cells commit to a differentiated state, and how this is coordinated with a permanent arrest of cell division. To address these questions, we will perform detailed quantitative analyses of native cells during their differentiation trajectory in the round worm Caenorhabditis elegans (C. elegans), in combination with sophisticated genetic manipulation. This project is part of a consortium effort and incorporates the latest technologies in transcriptome, epigenome, and proteome analysis, in close collaboration with specialists in single-cell analysis (Korswagen and van Oudenaarden labs, Hubrecht Institute), proteomics techniques (Vermeulen lab, Radboud University Nijmegen) and computational modeling (ten Tusscher lab, Utrecht University).

You, as post-doctoral researcher, will become part of the highly interactive Developmental Biology community at Utrecht University. This will include daily interactions with fellow researchers in the van den Heuvel, Boxem and Ruijtenberg labs, with graduate students and post-docs who work on related topics with one of the consortium partners, and with other researchers within the Institute of Biodynamics and Biocomplexity (e.g.: Akhmanova, Kapitein, Baubec, ten Tusscher labs) or broader Utrecht University campus.

Specifications

Utrecht University

Requirements

We are looking for a curious and dedicated scientist. We would also like you to bring the following qualifications

  • a PhD degree in Biology, Biomedical Sciences, or a related field;
  • a strong interest in molecular biology;
  • previous experience with independent research, and preferably with genetic model organisms, advanced microscopy, and/or bioinformatic data analysis;
  • training in scientific writing, communication and presentation in English;
  • motivation to work on a challenging project in a multidisciplinary and international research team.

Conditions of employment

  • a full time position for a year, which can be prolonged after a positive evaluation;
  • embedding in a great team of top Life Sciences researchers;
  • a full-time gross salary, depending on previous qualifications and experience, that ranges between €2,960 and €5,439 per month (scale 10 /11) Collective Labour Agreement Dutch Universities;
  • benefits including 8% holiday bonus and 8.3% end-of-year bonus;
  • pension scheme, partially paid parental leave, and flexible employment conditions (based on the Collective Labour Agreement Dutch Universities).

In addition to the employment conditions laid down in the cao for Dutch Universities, Utrecht University has a number of its own arrangements. For example, there are agreements on professional development, leave arrangements and sports. We also give you the opportunity to expand your terms of employment yourself via the Employment Conditions Selection Model. This is how we like to encourage you to continue to grow.

For more information, please visit working at the Faculty of Science.

Employer

Research in the Developmental Biology division makes use of a multidisciplinary strategy in genetic animal model systems (C. elegans, zebrafish, organoids) to acquire a deeper fundamental understanding of the processes that determine development and health. Three teams that use the C. elegans model work closely together and share experience in C. elegans genetics and biology, as well as technologies (latest CRISPR knock-in/knockout strategies, live imaging, advanced microscopy) on a daily basis. In addition, there are frequent interactions and joint lab meetings with neighbouring labs (Cell Biology, Neurobiology, Biophysics), and other groups (Genome Biology and Epigenetics, Theoretical Biology and Bioinformatics) in the Institute of Biodynamics and Biocomplexity  (IBB).

Research within the department of Biology is organized in two institutes: the Institute of Biodynamics and Biocomplexity (IBB) and the Institute of Environmental Biology (IEB). The department of Biology coordinates the teaching of the Bachelor’s programme in Biology, as well as Master’s programmes and PhD courses that are offered through the Graduate School of Life Sciences.

At the Faculty of Science there are 6 departments to make a fundamental connection with: Biology, Chemistry, Information and Computing Sciences, Mathematics, Pharmaceutical Sciences and Physics. Each of them is made up of distinct institutes which work together to focus on answering some of humanity’s most pressing problems. More fundamental still are the individual research groups - the building blocks of our ambitious scientific projects.

Utrecht University is a friendly and ambitious university at the heart of an ancient city. We love to welcome new scientists to our city – a thriving cultural hub that is consistently rated as one of the world’s happiest cities. We are renowned for our innovative interdisciplinary research and our emphasis on inspirational research and excellent education. We are equally well-known for our familiar atmosphere and the can-do attitude of our people. This fundamental connection attracts Researchers, Professors and PhD candidates from all over the globe, making both the University and the Faculty of Science a vibrant international and wonderfully diverse community.

Specifications

  • Postdoc
  • Natural sciences
  • 38—40 hours per week
  • €2960—€5439 per month
  • Doctorate
  • 1192730

Employer

Location

Padualaan 8, 3584 CH, Utrecht

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