At the Toxicology Division of the Institute for Risk Assessment Sciences (IRAS), we aim to improve the scientific basis of chemical risk assessment through fundamental and applied innovative research, teaching and training in mechanistic and predictive toxicology. We are looking for an enthusiastic and creative technician to achieve these goals and strengthen our Toxicology Division, which is made up of 4 research groups: Endocrine, Immune and Neurotoxicity and Exposure Assessment. You will be working mainly in the Endocrine Toxicology Research Group. This research group is focused on investigating the cellular and molecular mechanisms of action of endocrine disrupting chemicals using in vitro approaches and zebrafish. You will support students and (PhD) researchers working on diverse projects that aim to investigate the potential adverse effects of diverse environmental chemicals on endocrine-related disease and disorders. Examples of these projects include the European projects GOLIATH, AURORA and the Partnership for the Assessment of Risks from Chemicals (PARC).

You will work with various advanced in vitro models (cell lines, primary cells, stem cells) and different culture conditions (2D, 3D, barrier models) to elucidate if environmental chemicals can ultimately disrupt the endocrine system leading to adverse effects. Additionally, you will work with zebrafish larvae to elucidate affected endocrine mechanisms after exposures at the level of an entire organism. You will use various techniques, ranging from PCR, and cell bioassays to cellular imaging (fluorescence microscopy) and bioinformatics analyses. In addition, an important part of your work will involve taking responsibility for general laboratory maintenance as well as duties such as ordering, management of instruments, and maintenance of our electronic lab journal system. You will work in a team with other technicians to ensure the smooth operation of the labs.

• a Bachelor of Applied Science (BASc)/HLO degree (or equivalent) in the field of life and/or biomedical sciences, with a strong interest in cell biology, toxicology and data analysis;
• at least five years of experience working in a lab and demonstrated experience with cell culture techniques, molecular analysis and cellular imaging techniques;
• affinity with software, data analyses, and statistics is a plus;
• qualities such as accuracy, responsibility, reliability and being good at teamwork;
• good verbal and written communication skills in English;
• a diploma on animal experimentation (EU function A+C; ex. art. 13f.2) is an advantage.

We offer a temporary position (0.8 - 1.0 FTE) for one year in an international working environment. After positive evaluation, this can be turned into a permanent position. The gross salary - depending on previous qualifications and experience - ranges between €2,471 and €4,257 (scale 7-9 according to the Collective Labour Agreement Dutch Universities) per month for a full-time employment. Salaries are supplemented with a holiday bonus of 8% and a year-end bonus of 8.3% per year.

In addition, Utrecht University offers excellent secondary conditions, including an attractive retirement scheme, (partly paid) parental leave and flexible employment conditions (multiple choice model). For more information, please visit working at Utrecht University.

A better future for everyone. This ambition motivates our scientists in executing their leading research and inspiring teaching. At Utrecht University, the various disciplines collaborate intensively towards major societal themes. Our focus is on Dynamics of Youth, Institutions for Open Societies, Life Sciences and Sustainability.

The Faculty of Veterinary Medicine has a unique position in the Netherlands. Not only is this the only institution where veterinarians are trained, researchers are also working together on innovative scientific research. In addition, the faculty provides specialist clinical care. Thanks to this position, the Faculty of Veterinary Medicine is a point of contact for all veterinary matters, both nationally and increasingly internationally. The faculty employs approximately 900 veterinarians, scientists and support staff and counts 1.500 students.