We are looking for two highly qualified and motivated PhD candidates in Cognitive Neuroscience. The two positions are part of an ERC consolidator grant titled "Towards understanding human consciousness: How internal brain states and environmental context shape our subjective experience". Both PhD positions are embedded in the
Conscious brain lab, and the projects will be supervised by dr. Simon van Gaal and colleagues. The conscious brain lab consists of several PhD students, postdoctoral researchers and staff members of the Brain and Cognition department (department of Psychology) of the UvA who all study the neural basis of conscious and/or related topics (see website for details).
The two projectsProject 1: What makes us experience the world around us consciously? We do not become conscious of all inputs that reach our senses at every point in time: much processing goes on "under the radar". The aim of this project is to elucidate the neurochemical basis of conscious experience and to dissociate it from unconscious processes. Conscious experience will be manipulated in several ways (e.g., masking, rivalry) and different pharmaceutical agents are given to healthy human participants (on different days) while they are performing experimental tasks in which consciousness is manipulated. Pharmacological manipulations target GABAergic and Glutamatergic functioning to impede inhibitory and excitatory neural processes that are hypothesized to be important for conscious experience. EEG and fMRI will be used to measure the effects of these pharmacological interventions on neural processes indicative of feedforward, horizontal and feedback processing in the human brain.
Project 2:While studying consciousness, it is increasingly recognized that the goal to control as many "confounding factors" in lab experiments comes at a price. That is, in real life, conscious experience is not created in a controlled vacuum, but it is determined by internal spontaneous fluctuations in arousal and (responses to) external changes in environmental context. In this project we address how fluctuations in arousal and physical activity of the body (also referred to as "brain state") may shape sensory build-up of stimulus representations and hence conscious experience. Arousal fluctuations are measured when they fluctuate spontaneously using pupil size. However, arousal will also be manipulated by changes in physical activity of the body (e.g., by inducing drowsiness or active states in participants) and pharmacological intervention (up- and down regulating arousal). EEG and fMRI will be used to measure the neural effects of these manipulations and their impact on conscious experience.
Because in these projects pharmacological interventions are performed, one of the two candidates should be fluent in Dutch to be able to communicate well with the participants (in Dutch) (explaining/evaluating exclusion criteria etc.).
What are you going to do?
- complete and defend a PhD thesis within the official appointment duration of four years;
- gain knowledge of the field through literature survey, discussion with team members, and internal lab meetings;
- contribute to the design of experiments and perform experiments;
- analyse and interpret results of experiments;
- present data at local, national and international scientific meetings;
- assist in teaching undergraduates and Master's students and co-supervise junior scientists (technicians, MSc/BSc students).