This research project will be focused on risk factors and clinical neurological consequences of migraine. Migraine is an episodic disorder which is characterized by a severe headache and may be accompanied by nausea and/or light and sound sensitivity. It is one of the most common complaints encountered by neurologists in clinical practice. Despite the considerable burden on the patient as well as on healthcare systems, many aspects of the etiology and clinical consequences of migraine remain unknown. Especially risk factors in the field of lifestyle, circulating blood markers, and neuroimaging remain unexplored, but may substantially improve our understanding of the disease. Also, the risks of clinical neurological brain disease such as stroke or dementia following migraine remain elusive.

The PhD candidate will be working in the dynamic environment of the prospective population-based Rotterdam Study, and will be involved in data-collection related to migraine, lifestyle, and neuroimaging. The candidate will analyze the collected data in light of the specific research questions, and disseminate the findings through scientific articles and conference presentations. As part of the PhD-trajectory, the candidate will enter a Master of Science programme in Health Sciences at the Netherlands Institute of Health Sciences (Nihes).

We are seeking a highly motivated candidate with a master's degree in Medicine, Biomedical Sciences, Psychology, Epidemiology, or a related field. Experience with any of the following types of data or research questions would also be a strength: neurology; brain imaging (e.g. MRI); nutrition; risk factors. A strong command of English is required; knowledge of Dutch is helpful but not mandatory.

Being able to present a certificate of good conduct, a valid proof of identity, diploma's and/ or relevant registration such as BIG/ RGS are conditions for the appointment.

A Medical Doctor will be offered a position for 3,5 years; the gross monthly salary amounts a maximum of € 4.361,- (scale 10), depending on your relevant experience and based on a full-time working week of 36 hours. If you are appointed as a PhD you will receive a temporary position for 4 years. The gross monthly salary is € 2.357 ,- in the 1st year and increases to € 3.020,- in the 4th year (scale OIO). The terms of employment are in accordance with the Collective Bargaining Agreement for University Medical Centers (CAO UMC).

Erasmus MC

Erasmus MC stands for a healthy population and excellence in healthcare. By conducting groundbreaking work, we aim to push boundaries through leading the way in research, education and healthcare. We have access to the latest equipment and techniques in a state-of-the-art environment.

The candidate will be appointed at the Department of Epidemiology and will be mainly working in the Neuro-Epidemiology research unit. Historically, the main research focus of the Neuro-Epidemiology unit has been on common age-related brain pathologies, such as stroke and dementia, but during the past years the scope has been broadened to other common, burdening brain diseases of which migrain is a prominent one. The research will be conducted in the Rotterdam Study, an on-going population-based cohort study that began in 1990 and now follows nearly 15,000 older adults. More information on this study can be found on the Rotterdam Study website.