Postdoc quantitative analysis of large MRI data for bio-medical applications

Postdoc quantitative analysis of large MRI data for bio-medical applications

Published Deadline Location
17 Apr 3 May Wageningen

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Job description

We are looking for a post-doctoral researcher who will develop and apply new non-iterative, non-fitting, image analysis methods, based on the phasor approach, to be applied on large clinical data sets obtained by MRI and other imaging techniques. The ultimate goal of this project is to obtain a fast and quantitative characterization of multi-component phases in tissue-related model, and in vivo systems.

We invite applications for a 2-years post-doctoral position based at the Laboratory of Biophysics at Wageningen University, funded from a 4TU consortium on "Precision Medicine by integrating multi-scale functional imaging and advanced machine learning" including three other research groups in The Netherlands: Delft University of Technology, Eindhoven University of Technology and University of Twente.

Current MRI measurements have the disadvantages that data are over-sampled during signal acquisition, which often leads to unnecessary long measuring times and relatively low information density in big data collections. Moreover, the contrast between, for instance, healthy and malignant tissue in bio-medical MRI, can be small or even absent. The challenge of this post-doctoral project is to develop new imaging data-driven approaches based on phasor analysis, with the goal to contribute to ongoing efforts in speeding up MRI measurements by many modern concepts in signal acquisition, post-processing and visualization, like MR fingerprinting, parallel imaging, sparse sampling, and computer-aided analysis. This approach will also enable running more powerful data acquisition schemes in order to obtain an extended amount of information within the same measuring time.

This project follows-up on highly successful research lines that were established over the last years at the Laboratory of Biophysics in WUR in the field of phasor-MRI application to in vivo human-brain data (see Vergeldt et al, Scientific Reports 7 (2017) 861). The candidate will benefit from thorough liaising with the other partners of the 4TU consortium to cross-link physics- and data-driven workflows.

Specifications

Wageningen University & Research

Requirements

You are an ambitious and enthusiastic scientist. Your profile should signal:
  • A MSc/PhD degree in experimental or theoretical physics, physical chemistry, mathematics, material science, engineering, or a related discipline;
  • Research experience in image analysis and/or NMR/MRI method developments;
  • A strong interest in bio-medical, biological and/or soft matter applications of image analysis techniques;
  • A good command of the English language is essential.

Conditions of employment

A job at an organisation that will challenge you every day to provide our clients with the best possible solution. As a post-doctoral researcher you will be part of an ambitious team working on a wide range of issues with plenty of scope for initiative. Personal input and responsibility are an integral part of our culture.

We offer you a salary based on your expertise and experience with a maximum of € 4.274,- gross per month (scale 10 of the Collective Labour Agreement for Dutch Universities). We offer a temporary 2 year contract for 38 hours per week (fulltime), preferably per July 2019. You also have the opportunity to work 40 hours a week with additional holidays.

In addition we offer:
  • 8% holiday allowance and 8.3% fixed-year allowance;
  • Excellent training opportunities and secondary working conditions;
  • In consultation with colleagues flexible working hours and vacations can be settled so that an optimal balance between work and private is possible;
  • An excellent pension scheme via ABP;
  • 232 holiday hours, the ability to purchase and good supplementary leave arrangements and an individualized model to compose part of your working conditions and a bicycle plan;
  • You can make use of the sports facilities available on campus against a reduced fee
The program also includes:
  • If needed, a training in NMR/MRI methodologies relevant to the project, as well as in phasor-based image analysis methods;
  • Extensive collaboration and short-term stays in partner laboratories (secondments).

Employer

Wageningen University & Research

The Laboratory of Biophysics (www.bip.wur.nl/UK/) is an international research group with leading expertise in the development and application of spectroscopic and imaging techniques relevant to bio-/soft-matter science, and it provides access to advanced state-of-the-art NMR/MRI spectroscopy equipment at the MAGNEFY NMR research facility (https://www.wur.nl/en/Value-Creation-Cooperation/Facilities/MAGNEtic-resonance-research-FacilitY.htm).

The Agrotechnology & Food Sciences Group is part of Wageningen University & Research, an organisation that brings together fundamental and applied scientific research. We work on creating 'healthy food in a bio-based society' with private sector companies, research institutes and government agencies in the Netherlands and abroad. Our innovations play a crucial role in solving the major issues which affect society today. Entrepreneurship and professionalism are key in all that we do. In short, we are a major international employer offering considerable potential for your career.

Wageningen University & Research
Delivering a substantial contribution to the quality of life. That's our focus - each and every day. Within our domain of good and safe food & food production, food security and a healthy living environment, we search for answers to issues affecting society - such as sustainable food production, climate change and alternative energy. Of course, we don't do this alone. Every day, 5000 people work on 'the quality of life', turning ideas into reality, on a global scale.

Could you be one of these people? We give you the space you need.

For further information about working at Wageningen University & Research, take a look at:
https://www.wur.nl/en/Jobs.htm

Acquisition regarding this vacancy is not appreciated.

Specifications

  • Postdoc
  • Natural sciences
  • max. 38 hours per week
  • University graduate
  • 496732

Employer

Wageningen University & Research

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Location

Droevendaalsesteeg, 6708 PB, Wageningen

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