This project will mainly be carried out at the Department of Molecular Biology, and will include frequent visits to the Biomedical Primate Research Centre in Rijswijk. Our team (headed by Dr Richard Bartfai) aims at understanding how molecular mechanisms enable adaptation and support pathogenesis of malaria parasites. We have a strong background in the development and integration of innovative single-cell (multi-omics) technologies and apply these technologies to understand the biology of the deadly malaria pathogens.
The Department of Molecular Biology is part of the
Radboud Institute for Molecular Life Sciences (RIMLS-Science), which is one of the six research institutes of the Faculty of Science at Radboud University.
The overarching aim of RIMLS-Science is to decipher molecular mechanisms of disease. Research areas of RIMLS-Science include epigenetics, stem-cell and developmental biology, and computational biology. The central research theme is regulation of gene expression during development, in health and in disease. Important tools used at the institute include next-generation sequencing, mass spectrometry, single-cell and spatial multi-omics and computational analysis, as well as method development. To perform state-of-the-art research, RIMLS-Science operates its own wet-lab, omics and computational facilities. This fundamental and applied research in medical biology and molecular life sciences has clear links to more clinically oriented research programmes at departments within the Radboud university medical center. RIMLS-Science currently has about 60 researchers, providing a vibrant and international working environment.