Research technician antibody development

Research technician antibody development

Published Deadline Location
12 Apr 26 Apr Utrecht

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A 1-year position for a technician in a project that aims to develop blocking antibodies for checkpoint therapy in cancer. You will raise and screen antibodies against selected targets for binding and their ability to block receptor function.

Job description

We invite highly motivated candidates with experience in cell culture and antibody production to apply.

A healthy immune system clears microbes without damaging the body. For this purpose, immune cells are regulated by inhibitory receptors that serve as a break on activation. These receptors can also prevent efficient clearing of tumour cells. This project is focused on a few key newly identified targets for which we will develop antibodies in collaboration with UMAB. To make the first steps towards clinical application, you will screen antibodies for binding to cell-expressed receptors. You will also test their ability to block these receptors in functional assays.


University Medical Center Utrecht (UMC Utrecht)


Required skills:
  • Intrinsic interest and motivation for early-stage therapeutic development.
  • Experience in cell culture and flow cytometry-based assays.

Preferred skills:
  • Affinity with immunology.
  • Experience with assay design and trouble shooting.

Conditions of employment

The maximum salary for this position (36 - 36 hours) is € 4.052,00 gross per month based on full-time employment.

In addition, we offer an annual benefit of 8.3%, holiday allowance, travel expenses and career opportunities. The terms of employment are in accordance with the Cao University Medical Centers (UMC).


You will part of the Inhibitory Receptor Lab that is led by Dr. Michiel van der Vlist and Prof. Linde Meyaard. The Inhibitory Receptor Lab is situated in Center for Translational Immunology in the UMC Utrecht and is part of the Oncode Institute. At the Center for Translational Immunology, approximately 200 people study immune responses in all their facets. We have a state-of-the-art flow cytometry facility, imaging facility, protein facility and the antibody generation facility U-MAB, all set up to facilitate the best transitional research possible.

In the Inhibitory Receptor Lab a dynamic and international team studies immune inhibitory receptors in health and disease. Our basic research line focuses on identification and characterization of inhibitory receptors, their ligands and mechanism of action. We have a strong translational focus to apply our knowledge in the clinic to cure patients. To foster this goal, research in our group covers the complete spectrum from academic basic to translational research, as well as public-private collaborative research. We strive for a diverse and inclusive working environment where we are kind to the person, but though on the data.
Please visit our website: for more information about our team.


  • Research, development, innovation
  • Health
  • max. 36 hours per week
  • max. €4052 per month
  • Higher professional education
  • 2024-4619


University Medical Center Utrecht (UMC Utrecht)

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Heidelberglaan 100, 3584CX, Utrecht

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