PhD on Treatment of Veterinary Patients with Liposomal Formulations

PhD on Treatment of Veterinary Patients with Liposomal Formulations

Geplaatst Deadline Locatie
18 jun 21 jul Utrecht
Are you passionate about nanoparticle formulation and their clinical application to veterinary patients? Then this PhD position is a great match for you!

Functieomschrijving

The treatment of leishmaniosis can cause toxicity. Encapsulating drugs in liposomes allows targeted delivery, reducing toxicity. This project aims to establish protocols and coordinate efforts to offer liposomal treatments to dogs with leishmaniosis. Liposomes with various lipid compositions and anti-leishmania drugs will be prepared and tested for quality and stability. Effective liposomes will be tested on infected canine macrophages for toxicity, efficacy, and uptake. The best formulation will be GMP-prepared, undergo quality control, and be tested for clinical efficacy in patients.

Wat ga je doen?
You will collaborate closely with veterinary clinicians and clinical pharmacists to develop protocols for the Good Manufacturing Practice (GMP) preparation of liposomal formulations. You take a lead role in the preparation and testing of liposomes with anti-leishmania drugs, focusing on quality control, stability, and efficacy.

You'll coordinate the project to offer liposomal treatments to veterinary patients, ensuring reproducibility and sterility of the final product. And evaluate the efficacy of liposomal formulations through clinical observation and parameter monitoring in veterinary patients.

Specificaties

Universiteit Utrecht

Functie-eisen

  • You put your collaboration and communication skills to good use. This means, for example, that you easily seek collaboration with other departments. You are keen on personal and professional development for yourself and people you work with.
  • You have proficiency in English language.
  • You have an MSc degree in pharmaceutical sciences, (biomedical) engineering, or related field (candidates nearing completion of their MSc are welcome to apply).
  • Prior experience with any of the following topics is beneficial but not required: (mammalian) cell culture, nanoparticle preparation, microfluidics, nanoparticle characterisation, flow cytometry, fluorescence microscopy

Arbeidsvoorwaarden

  • a position for one year, which will be extended by three years upon satisfactory performance;
  • a working week of 36 to 40 hours and a gross monthly salary between € 2.770,- and € 3.539,- in the case of full-time employment (salary scale P under the Collective Labour Agreement for Dutch Universities (CAO NU);
  • 8% holiday pay and 8.3% year-end bonus;
  • a pension scheme, partially paid parental leave and flexible terms of employment based on the CAO NU.

In addition to the terms of employment laid down in the CAO NU, Utrecht University has a number of schemes and facilities of its own for employees. This includes schemes facilitating professional development, leave schemes and schemes for sports and cultural activities, as well as discounts on software and other IT products. We also offer access to additional employee benefits through our Terms of Employment Options Model. In this way, we encourage our employees to continue to invest in their growth. For more information, please visit Working at Utrecht University.

Werkgever

Universiteit Utrecht

A better future for everyone. This ambition motivates our scientists in executing their leading research and inspiring teaching. At Utrecht University, the various disciplines collaborate intensively towards major strategic themes. Our focus is on Dynamics of Youth, Institutions for Open Societies, Life Sciences and Pathways to Sustainability. Sharing science, shaping tomorrow.

At the Faculty of Veterinary Medicine we train the veterinarians and researchers of the future, provide care for animals and conduct leading and societal relevant research. That is what we are good at. We see that the health and welfare of animals, humans and the environment are interconnected. By sharing our knowledge and working together, we make positive impact, both nationally and internationally. Our 1,500 students and 950 staff members inspire and strengthen each other. Our engagement connects us. The drive to, from an integral perspective, make the world a better place.

Our group is embedded in the Immunology group. You will collaborate closely with the department of Pharmaceutics for formulation and testing of liposomes, veterinary clinicians at the department of Clinical Sciences, and the pharmacy to develop protocols for GMP preparation of liposomal formulations. As a team, we prioritise effective collaboration, ongoing feedback, and both professional and personal development.

Additionele informatie

For more information, please contact Naomi Benne n.benne@uu.nl

Candidates for this vacancy will be recruited by Utrecht University.

Specificaties

  • PhD
  • Gezondheid
  • 36—40 uur per week
  • €2770—€3539 per maand
  • Universitair
  • 4010

Werkgever

Universiteit Utrecht

Lees meer over deze werkgever

Locatie

Yalelaan 1, 3584CL, Utrecht

Bekijk op Google Maps

Interessant voor jou

X

Solliciteer op deze vacature

Solliciteer op deze vacature

Dit sollicitatieproces wordt beheerd door de werkgever (Universiteit Utrecht). Heb je nog aanvullende vragen over jouw sollicitatie, neem dan contact op met de werkgever.

Bedankt voor je sollicitatie

Voor vragen over jouw sollicitatie kun je contact opnemen met de werkgever.

Tip: sla deze vacature op als favoriet in je AcademicTransfer account. Zo heb je meteen een overzicht en kun je de vacature makkelijk terugvinden. Nog geen account? Maak deze dan nu aan en profiteer van nog meer handige functionaliteiten!

Sollicitatieprocedure

As Utrecht University, we want to be a home for everyone. We value staff with diverse backgrounds, perspectives and identities, including cultural, religious or ethnic background, gender, sexual orientation, disability or age. We strive to create a safe and inclusive environment in which everyone can flourish and contribute.

To apply, please send your curriculum vitae, including a letter of motivation, via the ‘apply now’ button.

Sollicitatieprocedure

Sollicitatieprocedure

As Utrecht University, we want to be a home for everyone. We value staff with diverse backgrounds, perspectives and identities, including cultural, religious or ethnic background, gender, sexual orientation, disability or age. We strive to create a safe and inclusive environment in which everyone can flourish and contribute.

To apply, please send your curriculum vitae, including a letter of motivation, via the ‘apply now’ button.

Solliciteer uiterlijk op 21 jul 2024 23:59 (Europe/Amsterdam).