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During simultaneous drug delivery to neonates via infusion pump systems undesired and harmful dosing errors can occur, by a combination of low flow levels and relatively high medicine concentrations. In this project, the application of a multi-parameter chip is investigated for locally determining the composition of the infusion fluid just before it is introduced into the patient. The chip measures the composition by analysis of the physical parameters of the fluid. By comparing these properties with the expected values based on the set point of the pumps, drug administration can be carried out with higher confidence, yielding a better clinical result. Various sensors are integrated on the multiparameter chip, which make it possible to determine a number of physical properties of the gas or liquid, such as density, viscosity and specific heat, in addition to the flow velocity and the pressure. If these properties of the individual liquids are sufficiently different, it is possible to determine the mixing ratio for mixtures on the basis of an analytical model: solving n equations with n unknowns. Within this project it will be investigated whether the mentioned chip technology is indeed suitable for the intended application. To this end, applicants want to address the following research questions:
The University of Twente. We stand for life sciences and technology. High tech and human touch. Education and research that matter. New technology which leads change, innovation and progress in society. The University of Twente is the only campus university of the Netherlands; divided over five faculties we provide more than fifty educational programmes. We have a strong focus on personal development and talented researchers are given scope for carrying out groundbreaking research.
We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status or disability status. Because of our diversity values we do particularly support women to apply.
The faculty of Electrical Engineering, Mathematics and Computer Science (EEMCS) comprises three disciplines that shape Information and Communication Technology. ICT is more than communication. In almost every product we use mathematics, electronics and computer technology and ICT now contributes to all of societies' activities. The faculty works together intensively with industrial partners and researchers in the Netherlands and abroad and conducts extensive research for external commissioning parties and funders. The research which enjoys a high profile both at home and internationally, has been accommodated in the multidisciplinary research institutes MESA+, CTIT and MIRA.
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