Join us - we look forward to welcome you to our Self-Organizing Soft Matter Research Group at Eindhoven University of Technology!
We are seeking a highly motivated Postdoctoral Researcher with a passion for quantitative microscopy and single molecule studies to join our team to study the behavior of ice-binders at ice/water interfaces and how this relates to their activity. In this exciting role, you will be working in a vibrant and international research group aiming to identify structure-activity relations for natural and man-made ice-binders to reverse engineer novel materials tailored to block ice growth, slow down ice recrystallization, and/or promote ice nucleation as desired.
Eindhoven University of Technology
- Conduct high quality, curiosity-driven, original and independent research focusing on quantitative super-resolution microscopy
- Collaborate with a multi-disciplinary team of scientists and engineers
- Present research findings at conferences and publish in top-tier scientific journals
- Mentor and support junior researchers in the lab
Eindhoven University of Technology (TU/e) is one of Europe's leading research universities.
The Eindhoven area, in the southern part of the Netherlands, is one of Europe's top 'innovation ecosystems', with many high-tech companies and institutes. TU/e is intertwined with many of these companies and institutes, and research at TU/e is characterized by a combination of academic excellence, industrial relevance and societal interweaving.
Eindhoven University of Technology is a community of scientists, supporting staff, students and partners. People are the heart and soul of TU/e, so it is of great importance to safeguard the distinctive Eindhoven atmosphere, creating a personal, welcoming and vibrant environment that enables individuals and groups to grow professionally and personally.
The department Chemical Engineering and Chemistry is one of the nine departments of Eindhoven University of Technology. It was established in 1957, shortly after the university was founded. The department is located in the Helix and Matrix buildings on the TU/e campus. The candidate will closely collaborate with researchers within the departments of Chemical Engineering and Chemistry, Biomedical Engineering, Applied Physics, and the Institute for Complex Molecular Systems, all of which are located on the TU/e campus at walking distance.Job Description
Ice-binding proteins (IBPs) are natural ice-binders that offer protection against freezing to survive at subzero temperatures. Our group aims to unravel how biological and engineered ice-binders function, so that we can create customized chemical cryoprotectants for biomedical and other applications. We do not yet know how natural and synthetic ice-binders work, but it is clear that their activity is closely related to the way in which they interact with ice. Recently, we reported sub-zero nanoscopy experiments which allowed us to study for the first time the interfacial dynamics of ice-bound IBPs at the single molecule level (see PNAS publication
for more information). In this project you will build upon these pioneering experiments to study the interaction with ice of biological and engineered ice-binders at the single molecule level aiming to better understand how these block ice growth, shape ice crystals, inhibit ice recrystallization and control ice nucleation. You will work in close collaboration with other group members, who design, prepare, and/or study biological and (bio)synthetic ice-binders and explore their potential in cryopreservation and other applications.