Challenge: Developing a microfludic platform for systematic research on thrombus formation and thrombus-specific response to clot-dissolving drugs

Impact: Patient-specific treatment for thromboembolic diseases

Blood clots (Thrombi) are the main reason for heart attack and stroke. However, the dynamics of the clot formation and subsequent obstruction of blood vessels are not well understood, due to the significant complexity of their formation, which includes variations in blood composition and fluid dynamics within individuals.

Your role:

You will work between two departments, the Biomechanical Engineering (BME) and the Process and Energy (P&E) departments. In collaboration with Dr. Hanieh Bazyar (chemical engineering department), you will develop a microfluidic device, design and perform a controlled study to uniquely characterize thrombus formation, mechanical properties of the thrombi and their adhesion to vessel wall, and thrombus response to lysis drugs. You will use microscopic imaging techniques to look at microstructure during tests. Embedded in between the two departments you'll find a collaborative, open and friendly atmosphere and a large set of facilities.

You are an outstanding and enthusiastic researcher who has expertise and/or interest in one or more of the following areas: (Bio)mechanical Engineering, Chemical Engineering, Material Engineering or related disciplines. You understand that experimental work takes a strong basis on theoretical work and are perseverant in conducting and debuging experiments. You have obtained a PhD or an equivalent degree or expect to obtain an PhD very soon.

Good spoken and written English and the ability to work in a team are mandatory.

Please highlight your specific skills for this position explicitly in your motivation letter. Motivation letters that do not address any of these requirements will not be considered. 

Fixed-term contract: 1 year.

Salary and benefits are in accordance with the Collective Labour Agreement for Dutch Universities (salary indication: € 4.036 - € 5.090  per month gross). The TU Delft offers a customisable compensation package, discounts on health insurance, and a monthly work costs contribution. Flexible work schedules can be arranged.

For international applicants, TU Delft has the Coming to Delft Service. This service provides information for new international employees to help you prepare the relocation and to settle in the Netherlands. The Coming to Delft Service offers a Dual Career Programme for partners and they organise events to expand your (social) network.

This postdoc position has a fixed-term contract of 12 months.

Delft University of Technology

Delft University of Technology is built on strong foundations. As creators of the world-famous Dutch waterworks and pioneers in biotech, TU Delft is a top international university combining science, engineering and design. It delivers world class results in education, research and innovation to address challenges in the areas of energy, climate, mobility, health and digital society. For generations, our engineers have proven to be entrepreneurial problem-solvers, both in business and in a social context.

At TU Delft we embrace diversity as one of our core values and we actively engage to be a university where you feel at home and can flourish. We value different perspectives and qualities. We believe this makes our work more innovative, the TU Delft community more vibrant and the world more just. Together, we imagine, invent and create solutions using technology to have a positive impact on a global scale. That is why we invite you to apply. Your application will receive fair consideration.

Challenge. Change. Impact!

Faculty Mechanical, Maritime and Materials Engineering

From chip to ship. From machine to human being. From idea to solution. Driven by a deep-rooted desire to understand our environment and discover its underlying mechanisms, research and education at the 3mE faculty focusses on fundamental understanding, design, production including application and product improvement, materials, processes and (mechanical) systems.

3mE is a dynamic and innovative faculty with high-tech lab facilities and international reach. It’s a large faculty but also versatile, so we can often make unique connections by combining different disciplines. This is reflected in 3mE’s outstanding, state-of-the-art education, which trains students to become responsible and socially engaged engineers and scientists. We translate our knowledge and insights into solutions to societal issues, contributing to a sustainable society and to the development of prosperity and well-being. That is what unites us in pioneering research, inspiring education and (inter)national cooperation.

Click here to go to the website of the Faculty of Mechanical, Maritime and Materials Engineering. Do you want to experience working at our faculty? These videos will introduce you to some of our researchers and their work.