Eindhoven University of Technology (TU/e) is seeking a bright post-doctoral researcher to employ DNA nanotechnology to understand the biophysical principles behind antigen recognition by immune cells. Work in this area builds on expertise in the group on the positioning of proteins on DNA origami (Nat. Catal. 2019, J. Am. Chem. Soc. 2021). Work in this area is expected to result in rational design rules for the development of nano-vaccines. The successful candidate should be excited about applying nanotechnology solutions to uncover basic biophysical design principles that involve protein-protein recognition events. Post-doctoral research will be part of wider and exciting efforts currently spearheaded within the Synthetic Biology group led by prof. Tom de Greef.

We are accepting applications from enthusiastic and highly talented candidates who are interested in a dynamic, stimulating, and ambitious environment to perform their research.
We are looking for candidates that meet the following requirements:

• PhD in chemical biology, DNA nanotechnology, molecular biology or a comparable domain.
• Prior experience with recombinant protein expression and DNA nanotechnology.
• Prior experience with computer-based quantification/analysis tools (Matlab or similar).
• Ability to conduct high quality academic research, demonstrated for instance by a relevant PhD thesis and/or publication(s).
• Excellent mastering of the English language, good communication and leadership skills. Note that there is no Dutch language requirement.
• A research-oriented attitude with an analytical mindset.
• Be a team player and able to work in a dynamic, interdisciplinary context.

• A meaningful job in a dynamic and ambitious university with the possibility to present your work at international conferences.
• A full-time employment for two years, with an intermediate evaluation (go/no-go) after one year.
• The start date would ideally be 1 February 2022, but is slightly flexible.
• You will have free access to high-quality training programs on general skills, didactics and topics related to research and valorization.
• A gross monthly salary and benefits (such as a pension scheme, pregnancy and maternity leave, partially paid parental leave) in accordance with the Collective Labor Agreement for Dutch Universities.
• Additionally, an annual holiday allowance of 8% of the yearly salary, plus a year-end allowance of 8.3% of the annual salary.
• Should you come from abroad and comply with certain conditions, you can make use of the so-called '30% facility', which permits you not to pay tax on 30% of your salary.
• A broad package of fringe benefits, including an excellent technical infrastructure, moving expenses, and savings schemes.
• Family-friendly initiatives are in place, such as an international spouse program, and excellent on-campus children day care and sports facilities.