Postdoctoral position: Immunomodulatory effect of lipid transporters in Alzheimer's disease (AD)

Postdoctoral position: Immunomodulatory effect of lipid transporters in Alzheimer's disease (AD)

Published Deadline Location
15 Jan 29 Jan Maastricht

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For this Postdoctoral position, the role of CERT and its several domains in immunomodulation will be investigated in microglia, neurons, and astrocytes in a transgenic AD mouse model.

Job description

Tasks and Responsibilities:
  • Be able to set up, perform, and monitor research project outlines.
  • Experience with molecular biology techniques including AAV, lentivirus, cell culture, primary cell culture, and qPCR.
  • Mentor, stimulate, and connect PhD candidates throughout their project trajectory.
  • Help with writing and submitting research proposals and academic papers.
  • Possess, or be open to acquiring, an Article 9 certificate to conduct animal research. Experience working with animal including setting up animal experiments, minimally invasive procedures, and behavioral testing.
  • Collaborate with and report to (other) research teams, departments, manufacturers, and funding bodies.
  • Good professional and communication skills, showing effective teamwork within the organization.

Specifications

Maastricht University (UM)

Requirements

Selection Criteria:
  • A highly motivated candidate.
  • Scientific knowledge and interest in the field of neuroscience and inflammation.
  • A PhD degree in neuroscience, biomedical sciences, or another related discipline with a proven track record of authoring high-quality papers.
  • Intrinsic interest to get to the core of a problem, particularly in AD and the scope of translational research.
  • Willingness to collaborate in an efficient working style, strong communication skills, and enthusiasm for interaction with our patient user group are further prerequisites.

Conditions of employment

What we offer

As Postdoc at Faculty of Health, Medicine and Life Sciences, you will be employed by the most international university in the Netherlands, located in the beautiful city of Maastricht. In addition, we offer you:
  • Good employment conditions. The position is graded in scale 11 according to UFO profile Onderzoeker, with corresponding salary based on experience ranging from € 4,332 and € 5,929 gross per month (based on a full-time employment of 38 hours per week). In addition to the monthly salary, an 8.0% holiday allowance and an 8.3% year-end bonus apply.
  • An employment contract for a period of 12 months with a scope of 1.0 FTE. Upon a positive evaluation, an extension of 1 year will follow.
  • At Maastricht University, the well-being of our employees is of utmost importance, we offer flexible working hours and the possibility to work partly from home if the nature of your position allows it. You will receive a monthly commuting and internet allowance for this. If you work full-time, you will be entitled to 29 vacation days and 4 additional public holidays per year, namely carnival Monday, carnival Tuesday, Good Friday, and Liberation Day. If you choose to accumulate compensation hours, an additional 12 days will be added. Furthermore, you can personalize your employment conditions through a collective labor agreement (CAO) choice model.
  • As Maastricht University, we offer various other excellent secondary employment conditions. These include a good pension scheme with the ABP and the opportunity for UM employees to participate in company fitness and make use of the extensive sports facilities that we also offer to our students.
  • Last but certainly not least, we provide the space and facilities for your personal and professional development. We facilitate this by offering a wide range of training programs and supporting various well-established initiatives such as 'acknowledge and appreciate'.

The terms of employment at Maastricht University are largely set out in the collective labor agreement of Dutch Universities. In addition, local provisions specific to UM apply. For more information, click here.

Employer

Maastricht University

Why work at Maastricht University?

At Maastricht University (UM), everything revolves around the future. The future of our students, as we work to equip them with a solid, broad-based foundation for the rest of their lives. And the future of society, as we seek solutions through our research to issues from all around the world. Our six faculties combined provide a comprehensive package of study programmes and research.

In our teaching, we use the Problem-Based Learning (PBL) method. Students work in small groups, looking for solutions to problems themselves. By discussing issues and working together to draw conclusions, formulate answers and present them to their peers, students develop essential skills for their future careers.

With over 22,300 students and more than 5,000 employees from all over the world, UM is home to a vibrant and inspiring international community.

Are you drawn to an international setting focused on education, science and scholarship? Are you keen to contribute however your skills and qualities allow? Our door is open to you! As a young European university, we value your talent and look forward to creating the future together.

Department

Faculty of Health, Medicine and Life Sciences

At the Faculty of Health, Medicine and Life Sciences (FHML), everything revolves around healthy living. Our research and education are not solely focused on recovery, but place a strong emphasis on prevention, health preservation, and health promotion. Our aim is to use our knowledge and expertise to genuinely contribute to the well-being of individual people as well as society in total.

In, research, and healthcare, FHML is closely collaborating with the academic hospital in Maastricht, together forming the Maastricht University Medical Center (MUMC+). FHML is strongly connected in education, research, and care with the Maastricht academic hospital, together with which it forms the Maastricht University Medical Centre (MUMC+).

FHML, which is the largest faculty of Maastricht University, is formed by an (inter)national community of employees and students. The faculty offers a wide range of Dutch and English-taught bachelor's and master's programs in innovative educational concepts in which the emphasis is always on building bridges to practice.

The multidisciplinary research of the FHML focuses on a number of carefully chosen topical current themes. In addition to research aimed at gaining new insights, it also concerns research whose results can be directly translated into concrete applications and innovations. The implementation of the various research programs is organized in our six graduate schools and two institutes.

The School of Mental Health and Neuroscience (MHeNs)

https://www.maastrichtuniversity.nl/research/school-mental-health-and-neuroscience) dedicates its research to unraveling mechanisms, causes, and treatments for diseases related to the CNS, sensory systems, and mental disorders. In the Department of Psychiatry and Neuropsychology of Maastricht University, the Neuroimmunology group, led by Prof. Dr. Pilar MarLnez (hCps://www.researchgroup-neuroim.com/), invesLgates sphingolipid metabolism and its dysregulaLon in AD pathogenesis and their effect on the immune system. Further the group focus on the characterizaLon of the ceramide transporter protein (CERT) which is impaired in AD brain, promoLng AD pathophysiology. The research team is acLvely engaged in neuroinflammaLon and autoimmunity and collaborates with the Maastricht University Medical Center + (MUMC+).

Specifications

  • Postdoc
  • Health
  • max. 38 hours per week
  • €4332—€5929 per month
  • University graduate
  • 556

Employer

Maastricht University (UM)

Learn more about this employer

Location

P. Debyelaan 25, 6229HX, Maastricht

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