This postdoctoral fellow position is externally funded and the candidate will study the molecular regulation of anti-tumor cytotoxic CD8+ T cells (CTL). The goal of this study is to understand the miRNA changes that occur with anti-tumor CTL failure and exploit these changes to devise strategies for enhancing CTL immunity to cancer. The candidate will further develop experimental mouse models to investigate the functions of non-coding RNAs in tumor specific CTL immunity, generate retroviral expression vectors to manipulate activities of miRNAs in vivo and contribute to the fundamental and translational research.

Ambitious candidates with a strong background and hands-on experience in the area of tumor immunology and molecular biology will be considered. Experience with mouse models (art.9), next generation sequencing and bioinformatics is highly desirable. The successful candidates must have a Ph.D., publications in leading peer-review journals and presentations at scientific conferences. Candidates are expected to work independently, be highly motivated and have team spirit. The candidate should have excellent oral and written communication skills.

Being able to present a certificate of good conduct is a condition for the appointment.

We offer a full-time contract of 36 hours per week in an inspiring and challenging work environment with excellent fringe benefits. You will receive a temporary position for 2 years. The gross monthly salary amounts a maximum of € 4.917,- (scale 11), depending on your level of education and relevant experience and based on a full-time working week of 36 hours. The terms of employment are in accordance with the Collective Bargaining Agreement for University Medical Centers (CAO UMC).

Erasmus MC

A healthy population and excellence in healthcare through research and education. This is what Erasmus MC stands for. Conducting groundbreaking work, pushing boundaries and leading the way. In research, education, and healthcare. We are practical people with a high level of expertise, working hard to improve and renew the healthcare of today and the public health of tomorrow.

The department of Immunology performs cutting edge basic and translational research, participates in patient care by performing laboratory diagnostics (laboratory for medical immunology) and supporting clinical immunology, and performs a wide range of educational activities. Major research focuses in the department span molecular to clinical immunology and includes the development and function of innate and adaptive immunity, autoimmunity, immune deficiencies, immunity to infection, neuroimmunology, and lymphoid malignancies. The department has state-of-the-art facilities and equipment that support basic and translational research. The department is involved in multiple international consortia and networks, which facilitate innovation and rapid implementation of new immunological concepts and technologies.