In this project new types of Nanodiscs will be employed to enable applications in vaccine development and screening in drug development. Several well-characterized and medically relevant membrane proteins will be produced and inserted into Nanodiscs. The constructs will be characterized with biophysical techniques and screening tests will be performed. Also, immunogenicity and toxicity of the new constructs will be determined. The postdoctoral researcher will be expected to carry out the biophysical characterization as well as to oversee the entire project, and will be collaborating closely with the technician appointed to this project for the production of the membrane proteins. The project is a collaboration of Leiden University, Batavia Biosciences and ZoBio, all located at the Leiden Bioscience Park. The postdoctoral researcher will be seconded for several months to Batavia Biosciences at their site in Boston, MA. The remainder of the work will be carried out at the Leiden Institute of Chemistry.

• PhD degree in Biophysics, Biochemistry or Molecular Biology;
• Ability to work independently in several research groups;
• Team player with initiative;
• Experience with membrane protein purification and Nanodiscs.

The duration of the project is three years. We offer a position, initially for one year and with the possibility of a renewal for two years based on good performance. Salary range from €2,588  to €4,084  gross per month (pay scale 10 in accordance with the Collective Labour Agreement for Dutch Universities).

Leiden University offers an attractive benefits package with additional holiday (8%) and end-of-year bonuses(8.3 %), training and career development and sabbatical leave. Our individual choices model gives you some freedom to assemble your own set of terms and conditions. Candidates from outside the Netherlands may be eligible for a substantial tax break. More at https://www.universiteitleiden.nl/en/working-at/job-application-procedure-and-employment-conditions.

Diversity
Leiden University is strongly committed to diversity within its community and especially welcomes applications from members of underrepresented groups.

Universiteit Leiden

Leiden is a typical university city, hosting the oldest university in the Netherlands (1575). The University permeates the local surroundings; University premises are scattered throughout the city, and the students who live and study in Leiden give the city its relaxed yet vibrant atmosphere.

Leiden University is one of Europe's foremost research universities. This prominent position gives our graduates a leading edge in applying for academic posts and for functions outside academia. More at https://www.universiteitleiden.nl/en/working-at.

https://www.universiteitleiden.nl/werken-bij

Faculty of Science

The Faculty of Science is a world-class faculty where staff and students work together in a dynamic international environment. It is a faculty where personal and academic development are top priorities. Our people are committed to expand fundamental knowledge by curiosity and to look beyond the borders of their own discipline; their aim is to benefit science, and to make a contribution to addressing the major societal challenges of the future.

The research carried out at the Faculty of Science is very diverse, ranging from mathematics, information science, astronomy, physics, chemistry and bio-pharmaceutical sciences to biology and environmental sciences. The research activities are organised in eight institutes. These institutes offer eight bachelor’s and twelve master’s programmes. The faculty has grown strongly in recent years and now has more than 1,300 staff and almost 4,000 students. We are located at the heart of Leiden’s Bio Science Park, one of Europe’s biggest science parks, where university and business life come together.

https://www.universiteitleiden.nl/en/science