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Our research focuses on the elucidation of the molecular mechanisms underlying hormonal-mediated regulation of solute and water transport processes in epithelia including kidney and small intestine. The major emphasis is currently on the epithelial calcium (TRPV5 & TRPV6), magnesium (TRPM6 & TRPM7) and water (Aquaporin 2) channels, salt transporters (NCC, ENaC) and succinate receptors that constitute instrumental solute transport pathways in epithelia. The current projects aim to investigate in detail the regulation of these transport activities in health and disease. To this end, a wide variety of cutting edge techniques will be applied including cell and molecular biological, genetics biochemical and physiological procedures.
Tasks and responsibilities
Scale 10: max € 55784 gross per year at full employment
The Radboud university medical center advances human knowledge by conducting biomedical, translational and clinical research in order to improve wellbeing.
Our key strength is medical life-sciences and clinical practice, with an impressive infrastructure comprising state-of-the-art technology platforms and (translational) research facilities. The Radboud university medical center is therefore uniquely positioned in the emerging Euregio and Dutch healthcare infrastructure to play a leading role in the new healthcare paradigm of prediction, prevention and personalised medicine.
The Radboud university medical center focuses on scientific health challenges of today, with an eye on emerging diseases of the future.
Our mission: ‘to have a significant impact on healthcare’.
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