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Sanquin Research’s Department of Immunopathology is looking for a highly motivated and ambitious immunologist.
The post-doc position is part of the Target-to-B! consortium, which is national consortium funded by the Top Sector Life Sciences & Health and the Dutch Collaborative Health Funds. The involvement and role of B cells and antibodies in the development of autoimmunity and cancer will be studied in a disease-overarching approach by several leading groups in the Netherlands.
The post-doc will investigate the routes of B cell differentiation towards formation of short-lived and long-lived plasma cells, in continuation of our ongoing research line. Plasma cell differentiation is being investigated using a combination of defined in vitro differentiation systems and ex vivo analyses of human blood and tissues and involve single cell RNAseq analyses and subsequent biomarker mining. The goal is to be able to identify and B cell differentiation and (pre-)plasma cell subsets and to analyze their functional potential in healthy persons upon vaccination and in patients suffering from autoimmune diseases that show B cell involvement.
The B cell Research group investigates the regulation T cell-dependent B cell differentiation and antigen-specific IgG responses. The group is part of the Department of Immunopathology in the Division Research of Sanquin. The department comprises 40-50 people (postdocs, PhD-students, undergraduate students and technicians) that all work on related research topics.
A unique research opportunity in a dynamic environment in an area where data science, clinical epidemiology and quality management meet.
Curious about this project? Read more about it, below the video.
Sanquin Blood Supply Foundation (Sanquin)
Plesmanlaan 125, 1066 CX, Amsterdam