You will become part of an international team of bioinformaticians, biologists and clinicians. Our research is dedicated to improve cancer immunotherapy by understanding how it modulates the immune system and tumor microenvironment of head and neck cancer patients and melanoma patients. Your project will focus on translational research, being part of state-of-the-art clinical intervention trials conducted in the Antoni van Leeuwenhoek hospital by analyzing bulk sequencing or single-cell sequencing data of patient tumor biopsies or peripheral blood.

The candidate should have a great interest to understand the biological and clinical questions related to this type of translational research. We are looking for a highly motivated and enthusiastic Postdoc with a PhD level in computer science, bioinformatics or systems biology. Experience with high-throughput data analysis in biology and at least some knowledge of basic (cancer) biology involved are mandatory. The candidate must have a good knowledge in multidimensional data analysis in biology; can define the most appropriate statistical bioinformatic approaches; and be proficient in high-level languages like Python or R. Familiarity with existing systems biology methods and software, and experience of collaboration with biologists for solving concrete biological problems would represent as strong advantages. Excellent communication skills and team spirit, and a capacity to work in autonomy are essential. All data analyses will be intensively discussed with co-investigators including clinicians. Fluency in spoken and written English is required.

Fixed-term contract: 4 jaar.

The Postdoc will be employed by the research groups of Dr. Lotje Zuur and Prof. Daniel Peeper, and will work under direct supervision of Dr. Oscar Krijgsman. We offer a contract for 4 years. The gross salary per month will range from € 3.375,- to € 4.111,- according to FWG-function group 55 and depends on previous experience. The terms of employment will be in accordance with the CAO Ziekenhuizen (Collective Labour Agreement for Hospitals).

Antoni van Leeuwenhoek

The Netherlands Cancer Institute - Antoni van Leeuwenhoek was established on October 10, 1913. The founders, Rotgans, professor of Surgery, De Bussy, publisher, and De Vries, professor of Pathology, wanted to create a cancer institute 'where patients suffering from malignant growths could be treated adequately and where cancer and related diseases could be studied'. They bought a house on one of the canals in Amsterdam and named it the 'Antoni van Leeuwenhoek Huis', after the famous Dutch microscopist. The clinic had room for 17 patients, while the laboratory could accommodate 8 to 10 scientists.