As research technician you will study the important roles of SUMOylation and ubiquitylation during cell cycle progression at a proteome-wide level and at the level of individual target proteins as part of a Vici innovation project funded by NWO. Furthermore, you will support the PI concerning lab management.

In short

·        You will work on a Vici innovation project funded by NWO.

·        This project has a duration of three years

·        You need to have experience with molecular biology

You have completed a college education in a relevant area. Besides, you have a strong background in protein purification, protein biochemistry, molecular biology, cell biology and mass spectrometry, in particular with Orbitrap technology. Prior experience with cell cycle progression and ubiquitin or ubiquitin-like proteins will be a distinct advantage. You are an enthusiastic, highly motivated, skilful, flexible, stress-resistant, organized and result-driven team player. You have excellent communication skills, both written and spoken in Dutch and English.

Fixed-term contract: 3 years.

You will be employed on the basis of 36 hours per week. Appointment is for 3 years. Your salary is based on your education and experience and is a maximum of  € 3,280  gross per month for a full time position (scale 7 in the Collective Labour Agreement for University Hospitals).

LUMC

At the Leiden University Medical Center, we continuously work on improving patient care. We invest in groundbreaking, international research and work with the latest equipment. Together with our team of doctors, medical specialists, teachers, academic researchers and supporting staff, we aim for the best quality in health care, education and international research. And we need you to realize our goals!

Cell & Chemical Biology

Within the department of Cell & Chemical Biology a team of professionals investigates functional regulation of proteins by post-translational modifications including SUMOylation, ubiquitylation and phosphorylation. This enables us to improve our knowledge about fundamental processes of life at the molecular level and to improve our knowledge about disease-linked de-regulation of these processes. More information is available on our website https://ccb.lumc.nl/