Are you a highly motivated student with a Master degree in Biomedical Sciences or a similar education level with interest in the complement system? Do you want to perform your PhD studies on unravelling the functions of Factor H and Factor H related proteins and implement them in a diagnostic tool?
Interested? Please, read further!
This project is part of a H2020 FET open consortium grant consisting of 8 partners located in different parts of Europe. The EU-funded SciFiMed project will study the Factor H family proteins' contributions to diseases aiming to obtain proof-of-principle for a multiplex detection system to simultaneously quantify and analyze the functional activity of all seven proteins in patient samples. This specific PhD project (which will start the 1th of January 2021) will aim to develop specific antibodies against the different FH family proteins. In addition, using CRISPR Cas9 whole genome screenings this project aims to determine specific cellular binding partners of the different FH family proteins and unravel the function of this binding. Moreover, we aim to determine expression levels of the FH family proteins in several disease cohorts.
We are looking for highly motivated individuals with:
Fixed-term contract: 4 jaar.
We offer unique research opportunities in a dynamic environment. Nowhere else in the world you will find an organization that combines medical, pharmaceutical, diagnostic and scientific research under one roof. In addition to a challenging project in a multi-disciplinary and enthusiastic team we offer:
Sanquin is een not-for-profit organisatie die de bloedvoorziening in Nederland verzorgt. Naast het afnemen, verwerken en uitgeven van bloedproducten, houdt Sanquin zich bezig met het maken van reagentia, het verrichten van onderzoek en het verzorgen van onderwijs.
The research project is embedded in the department of Immunopathology (IP) of Sanquin. Sanquin provides a lively, internationally oriented, scientific environment with excellent research facilities (flow cytometry, confocal microscopy, mass spectrometry, and sequencing). Research of the department IP focuses on the regulation of immune responses against non-infections antigens. The Complement Research group, part of the department IP, is headed by Dr. Ilse Jongerius and investigated the general aim of our research is to investigate how complement is regulated on different human host cells in health and disease. Next, we study how unwanted complement activation can be influenced in order to tip the balance back to normal and minimize or prevent damage to the host.
For more information about the position, please contact Hanneke Kroneman via (0)6 50073316. Submissions are open until 12th of October 2020. Apply by sending us your CV and your cover letter using the ‘Apply’ button below! A pre-employment screening will be a part of the procedure.
Sanquin does not accept unrequested help from bureaus for this vacancy. CV's (in whatever shape or form) that are send by mediation bureaus to any employee of Sanquin without a written assignment of a corporate recruiter, will be considered property of Sanquin and Sanquin will therefore not owe compensation in any way.
Sanquin Blood Supply Foundation (Sanquin)
Plesmanlaan 125, 1066 CX, Amsterdam
This application process is managed by the employer (Sanquin Blood Supply Foundation (Sanquin)). Please contact the employer for questions regarding your application.
Make sure to apply no later than 12 Oct 2020 23:59 (Europe/Amsterdam).
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