The trigger for Type 1 diabetes is not known, but evidence is emerging that suggests that the complete pancreas is affected in Type 1. The project addresses if anomalies in the exocrine pancreas may lead to beta cell stress. Key is to do this in a cause/ consequence approach using advanced microscopic tools and the zebrafish larvae as a model. This project is part of a ZonMW OPEN project of Dr Ben Giepmans (UMC Groningen), Dr Elizabeth Carroll (TU Delft) and Dr Arnaud Zaldumbide (LUMC). In addition to the Psost-doc position in Groningen, a PhD-student position on this project is open in Leiden/ Delft.

Further reading: https://www.nature.com/articles/s41467-020-16287-5

We are looking for a candidate (f/m), a postdoc with a PhD degree in molecular cell biology, preferably with experience in Life Sciences and Technology. Experience and/or interest in optical microscopy and the zebrafish larvae as a research model are required. You are a team player, highly motivated, self-driven, and have a high level of written and spoken English.

The conditions of employment comply with the Collective Labour Agreement of Medical Centers (CAO-UMC). The 0,80 fte position is for one year with a possibility for an extension till a maximum of 4 years. Salary indication for the postdoc position is scale 10, with a maximum salary amount of € 4.615 gross per month depending on your qualifications and experience, based on a full-time position. In addition, the UMCG will offer you 8% holiday pay and 8.3% end-of-year bonus.

How to apply
Full applications including a resume, a motivation letter and the contact information of at least 2 references will receive consideration if received before August 31, 2021. You can only apply using the digital application form at the UMCG website and upload the relevant documents. Applications using the indicated email-address will not be processed. Following your application, you will receive an email confirmation.

Biomedical Sciences of Cells & Systems (BSCS)

The research at the Department of Biomedical Sciences of Cells & Systems (BSCS) at the UMC Groningen focusses on understanding basic functions and processes of the cell & systems and how they lead to diseases if disturbed. The Department strives for identification and, if possible, exploitation of targets to prevent or cure disease, and to promote Healthy Aging. The position will part of an ZonMW-funded project on “Beta cell stress and the exocrine pancreas: A cause/ consequence relationship?” coordinated by dr. B. N.G. Giepmans. In the laboratory of dr. Giepmans advanced microscopic techniques are implemented to help to understand how molecular mechanisms lead to diseases, with a focus on the Islets of Langerhans malfunction in Type 1 diabetes.